c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
IV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreatic c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancerc cancerDaniel Delitto, Eva Vertes-George, Steven J Hughes, Kevin E Behms,Jose G TrevinoCITATIONDelitto D, Vertes-George E. Hughes SJ, Behrns KE. Trevino JG. C-Met signaling in the development of tumorigenesis and chemoresistance: Potential applications in pancreatic cancer. Worl d J Gastroenterol 2 c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer014; 20(26): 8458-8470URLhttp://www.wjgnet.com/1007-9327/full/v20/i26/8458.htmDOIhttp://dx.doi.org/10.3748/wjg.v20.i26.8458OPEN ACCESSArticles publishc-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
ed by this Open-Access journal are distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distributIV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreatic c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancericense.CORE TIPAs one of the leading causes of cancer-related deaths, pancreatic cancer remains elusive to our current therapeutic options. These modest advances in current therapies for pancreatic cancer have led to the recognition and development of targeted therapies toward tyrosine kinase recept c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancerors such as the C-Met receptor. In this review, we characterize the role of C-Met in the development of tumorigenesis, metastasis and chemoresistance,c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
highlighting the potential of C-Met as a therapeutic target in pancreatic cancer.KEY WORD sPancreatic adenocarcinoma; C-Met; Chemoresistance; ReceptoIV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreatic c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancerce(5) wjqnet.comNAME OF JOURNALWorld Journal of GastroenterologyISSN1007-9327 (print) 2219-2840 (online)PUBLISHERBaishideng Publishing Group Inc, 8226 Regency Drive, Pleasanton, CA 94588, USAWEBSITEhttp://www.wjgnet.comName of journal: World Journal of GastroenterologyESPS Manuscript NO: 5721 Column c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancers: TOPIC HIGHLIGHTC-Met signaling in the development of tumorigenesis and chemoresistance: Potential applications in pancreatic cancerDaniel Delitto,c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
Eva Vertes-George, Steven J Hughes, Kevin E Behrns, Jose G TrevinoDaniel Delitto, Steven J Hughes, Kevin E Behms, Jose G Trevino, Department of SurgerIV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreatic c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancere, Gainesville, FL 32610, United StatesAuthor contributions: All the authors contributed to this manuscript. Correspondence to: Jose G Trevino, MD. Department of Surgery, University of Florida-Gainesville, 1600 sw Archer Rd, Rm 6175, PO Box 100109, Gainesville, FL 32610, United States. jose.trevino@ c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancersurgery.ufl.eduTelephone: +1-352-2737967 Fax: +1-352-2650761Received: September 23, 2013 Revised: December 18, 2013 Accepted: April 1, 2014Published oc-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
nline: July 14, 2014AbstractPancreatic ductal adenocarcinoma is the 4th leading cause of cancer deaths in the United States. The majority of patients IV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreatic c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancerstance involves signaling via the mesenchymal-epithelial transition factor protein (MET), a previously established pathway critical to cell proliferation and migration. Here, we review the literature to characterize the role of MET in the development of tumorigenesis, metastasis and chemoresistance, c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer highlighting the potential of MET as a therapeutic target in pancreatic cancer. In this review, we characterize the role of C-Met in the developmentc-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
of tumorigenesis, metastasis and chemoresistance, highlighting the potential of C-Met as a therapeutic target in pancreatic cancer.c> 2014 Baishideng IV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreatic c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancerge E, Hughes SJ, Behrns KE, Trevino JG. C-Met signaling in the development of tumorigenesis and chemoresistance: Potential applications in pancreatic cancer. World J Gastroenterol 2014; 20(26): 8458-8470 Available from: URL: http://www.wjgnet.com/1007-9327/full/v20/i26/8458.htm DOI: http://dx.doi.or c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancerg/10.3748/wjg.v20.i26.8458Core tip: As one of the leading causes of cancer-related deaths, pancreatic cancer remains elusive to our current therapeutic-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer
c options. These modest advances in current therapies for pancreatic cancer have led to the recognition and development of targeted therapies toward tIV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreatic c-Met signaling in the development of tumorigenesis and chemoresistance Potential applications in pancreatic cancer and chemoresistance.IV d ợWorld Journal of GastroenterologyC-Met signaling in the development of turn origenesis and chemoresistance: Potential applications in pancreaticGọi ngay
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