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Nội dung chi tiết: synthetic-impacts-second-review-en

synthetic-impacts-second-review-en

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-enOF COMPONENTS, ORGANISMS AND PRODUCTS RESULTING FROM SYNTHETIC BIOLOGY TECHNIQUES ON THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITYINTRODUCTION1

In decision XI/11 on new and emerging issues relating to the conservation and sustainable use of biodiversity the Conference of the Parties took note synthetic-impacts-second-review-en

of the proposals for new and emerging issues relating to the conservation and sustainable use of biodiversity and requested the Executive Secretary' t

synthetic-impacts-second-review-en

o:(a)Invite Parties, other Governments, relevant international organizations, indigenous and local communities and other stakeholders to submit, in ac

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-eniology techniques that may have impacts on the conservation and sustainable use of biological diversity and associated social, economic and cultural c

onsiderations;(b)Compile and synthesize relevant available information, together with the accompanying information;(c)Consider possible gaps and overl synthetic-impacts-second-review-en

aps with the applicable provisions of the Convention, Its Protocols and other relevant agreements related to components, organisms and products result

synthetic-impacts-second-review-en

ing from synthetic biology techniques;(d)Make a synthesis of the above information, including an analysis of how the criteria set out in paragraph 12

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-enical and Technological Advice prior to the twelfth meeting of the Conference of the Parties, in accordance with paragraph 13 of decision IX/29:2In res

ponse this decision the Executive Secretary issued notification 2013-018 inviting additional information on synthetic biology and undertook a review o synthetic-impacts-second-review-en

f information in accordance with paragraph 5 of decision XI/12 with a view to enabling the Subsidiary Body on Scientific. Technical and Technological

synthetic-impacts-second-review-en

Advice to consider the proposal.3This note was made available for the information of the eighteenth meeting of the Subsidiary Body on Scientific, Tech

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-enJuly to September 2013, and in April 2014.4The study is accompanied by a second document focusing on gaps and overlaps with the applicable provisions

of the Convention and its Protocols (made available as UNEP/CBD/SBSTTA/18/INF/4 for the information of the eighteenth meeting of the Subsidiary Body o synthetic-impacts-second-review-en

n Scientific. Technical and Technological Advice).DRAFT FOR REVIEW - DO NOT CITEPage 2TABLE OF CONTENTSNEW AND EMERGING ISSUES RELATING TO THE CONSERV

synthetic-impacts-second-review-en

ATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS OF COMPONENTS. ORGANISMS AND PRODUCTS RESULTING FROM SYNTHETICBIOL

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-en...........................................................3I.TECHNICAL BACKGROUND ON SYNTHETIC BIOLOGY..................................61.3Areas of

synthetic biology research.................................91.4Current and near-termproducts involving synthetic biology.........13II RELEVANT INFORMA synthetic-impacts-second-review-en

TION ON COMPONENTS, ORGANISMS AND PRODUCTS RESULTING FROM SYNTHETIC BIOLOGY TECHNIQUES THAT MAY HAVE IMPACTS ON THE CONSERVATION AND SUSTAINABLE USE O

synthetic-impacts-second-review-en

F BIOLOGICAL DIVERSITY.....................182.1Applications of synthetic biology and their potential positive and negative impacts.182.2Biosafety con

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-enETIC BIOLOGY TECHNIQUES THAT MAY HAVE IMPACTS ON ASSOCIATED SOCIAL. ECONOMIC AND CULTURAL CONSIDERATIONS .............................................

..................... 353.1Biosecurity considerations relating to biodiversity................................353.2Economic considerations relating t synthetic-impacts-second-review-en

o biodiversity...................................373.3Human health considerations relating to biodiversity..............................413.4Ethical c

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onsiderations relating to biodiversity...................................423.5Intellectual property considerations related to biodiversity............

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-enf the most commonly cited definitions of synthetic biology is “the design and construction of new biological parts, devices, and systems” and “the re-

design of existing, natural biological systems for useful purposes.” Although there is no legally accepted definition, there is general agreement that synthetic-impacts-second-review-en

synthetic biology aims: to exercise control in the design, characterization and construction of biological pans, devices and systems, leading to more

synthetic-impacts-second-review-en

predictable designed biological systems. Key features of synthetic biology include chemical synthesis of genetic sequences and an engineering-based a

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-endescribed as a "converging technology,” synthetic biology brings together and builds on the fields of engineering, molecular biology, systems biology,

nanobiotechnology and information technology.2Products of synthetic biology arc often made using multiple techniques of syntheticbiology and “convent synthetic-impacts-second-review-en

ional” biotechnology more broadly. Currently, the majority of current and near-term commercial and industrial applications of synthetic biology use sy

synthetic-impacts-second-review-en

nthetic DNA-C ircuits and synthetic metabolic pathway engineering to create microbes that produce molecules for pharmaceuticals, fuels, chemicals, fla

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

synthetic-impacts-second-review-enngineering, genome-level engineering, protocell construction, and xenobiology. Some see the insertion of synthetically designed and produced DNA seque

nces or pathways into an existing genome largely as rebranding conventional biotechnology. Others consider the building of non-natural pathways that w synthetic-impacts-second-review-en

ould be difficult to achieve with traditional genetic engineering and the systematic engineering circuits and pathways as approaches novel to syntheti

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c biolog}' and distinct from traditional genetic engineering.

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

DRAFT FOR REPage INEW AND EMERGING ISSUES RELATING TO THE CONSERVATION AND SUSTAINABLE USE OF BIODIVERSITY - POTENTIAL POSITIVE AND NEGATIVE IMPACTS O

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