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Ebook Acute nephrology for the critical care physician: Part 2

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Nội dung chi tiết: Ebook Acute nephrology for the critical care physician: Part 2

Ebook Acute nephrology for the critical care physician: Part 2

Part IIIPrevention and ProtectionPrevention of AKI and Protection of the KidneyMichael Joannidis and Lui G. Forni11.1IntroductionAcute kidney injury (

Ebook Acute nephrology for the critical care physician: Part 2(AKI) poses a significant risk to patients resulting in an increase in both mortality and morbidity. As discussed in previous chapters, the major caus

es of AKI in the ICU include renal hypoperfusion, sepsis and septic shock, heart failure and direct nephrotoxicity although in most cases the aetiolog Ebook Acute nephrology for the critical care physician: Part 2

y is multifactorial with a combination of events leading to AKI. Major risk factors have been identified which predispose to the development of AKI (T

Ebook Acute nephrology for the critical care physician: Part 2

able 11.1). Given the poor outcomes of patients with AKI it is of the highest priority for physicians treating critically ill patients. Given that to-

Part IIIPrevention and ProtectionPrevention of AKI and Protection of the KidneyMichael Joannidis and Lui G. Forni11.1IntroductionAcute kidney injury (

Ebook Acute nephrology for the critical care physician: Part 2ajor issues:1Ensuring adequate renal perfusion2Modulation of renal physiology3Avoiding further, additional renal insultM. Joannidis. MD (0)Division of

Intensive Care and Emergency Medicine.Department of Internal Medicine. Medical University Innsbruck.Innsbruck A-6020. Austriae-mail: michael.jounnidi Ebook Acute nephrology for the critical care physician: Part 2

s@'i-med.ac.atL.G. ForniDepartment of Intensive Care Medicine. Royal Surrey County HospitalNH.S Foundation Trust, Surrey Perioperative Anaesthesia Cri

Ebook Acute nephrology for the critical care physician: Part 2

tical Care CollaborativeResearch Group (SPACeR) and Faculty of Health Care Sciences.University of Surrey. Guildford. UKe-mail: luifomi@nhs.net© Spring

Part IIIPrevention and ProtectionPrevention of AKI and Protection of the KidneyMichael Joannidis and Lui G. Forni11.1IntroductionAcute kidney injury (

Ebook Acute nephrology for the critical care physician: Part 22M. Joannidis and L.G. ForniTable 11.1 Major risk factors for AKIPatient factorsAdvanced Age Female Black RacePre-existing co-morbiditiesChronic Kidne

y Disease (CKD) Liver Disease Respiratory Disease Heart Failure Diabetes: Especially with proteinuria CancerCurrent susceptibilitiesVolume Depletion D Ebook Acute nephrology for the critical care physician: Part 2

ehydration HypoalbuminemiaExposuresCritical Illness Sepsis Circulatory Shock BurnsSurgeryCardiac Surgery (especially with CPB) TraumaDrugsNephrotoxic

Ebook Acute nephrology for the critical care physician: Part 2

Agents RadiocontrastAdapted front KDIGO11.2Ensuring Adequate Kidney PerfusionAccording to large cohort studies hypovolemia, sepsis and heart failure h

Part IIIPrevention and ProtectionPrevention of AKI and Protection of the KidneyMichael Joannidis and Lui G. Forni11.1IntroductionAcute kidney injury (

Ebook Acute nephrology for the critical care physician: Part 2ll as a trigger for this syndrome. However, the practicalities of how to provide optimal renal perfusion are far from straightforward but are best ach

ieved by a systematic approach with the main targets being:(a)Optimizing systemic haemodynamics Ebook Acute nephrology for the critical care physician: Part 2

Part IIIPrevention and ProtectionPrevention of AKI and Protection of the KidneyMichael Joannidis and Lui G. Forni11.1IntroductionAcute kidney injury (

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