Ebook Color atlas of oral diseases: Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Color atlas of oral diseases: Part 2
Ebook Color atlas of oral diseases: Part 2
8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2inical forms in which mucocutaneous lesions may occur with or without systemic manifestations.Discoid lupus erythematosus (DI.I:) is the more common form of the disease. It tends to be confined to the skin and has a benign course in the vast majority of patients. I he skin lesions are characterized Ebook Color atlas of oral diseases: Part 2by violaceous papules and patches, scaling, and prominent follicular hyperkeratosis. These lesions are sharply demarcated from the surrounding healthyEbook Color atlas of oral diseases: Part 2
skin and progress to scarring with atrophy and telangiectasia. Discoid lupus lesions arc very often located above the neck region (face, scalp, and c8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2cterized as generalized Di li. The cutaneous lesions persist for months to years.The oral mucosa is involved in 15 to 25% of the cases, usually in association with skin lesions. However, on rare occasions, oral lesions may occur alone.The typical oral lesions arc characterized by a well-defined cent Ebook Color atlas of oral diseases: Part 2ral atrophic red area surrounded by a sharp elevated border of irradiating whitish striae (Fig. 303). Telangiectases and small white dots may be preseEbook Color atlas of oral diseases: Part 2
nt on the erythematous areas. Ulcers, erosions, or while plaques may also be present and progress to atrophic scarring (Fig.304).The buccal mucosa is 8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2thognomonic.The differential diagnosis should include leukoplakia. erylhroplakia. lichen planus, geographic stomatitis, syphilis, and cicatricial pemphigoid.Laboratory tests. Serum antinuclear antibodies are infrequently present at low titers and anti-double-stranded DNA antibodies are rarely presen Ebook Color atlas of oral diseases: Part 2t. Subcpidcmial immunoglobulins arc delected in 75% of biopsy specimens of involved skin or mucosae, using fluorescent techniques. Histopathologic exaEbook Color atlas of oral diseases: Part 2
mination of oral lesions is also helpful.Treatment. The oral lesions of Di li are treated with local steroids if the lesions arc small or with systemi8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2y-llke eruption on the face.Fig. 303. Discoid lupus erythematosus, typical lesion on the buccal mucosa.Fig. 304. Discoid lupus erythematosus, ulcer on the lower lip.19021. Autoimmune DiseasesFig. 305. Systemic lupus erythematosus, multiple erosions surrounded by a whitish or reddish zone.Systemic Lu Ebook Color atlas of oral diseases: Part 2pus ErythematosusSystemic lupus erythematosus (SLE) is a serious systemic disease involving the skin, mucosae, cardiovascular and gastrointestinal sysEbook Color atlas of oral diseases: Part 2
tems, lungs, kidneys, joints, and nervous system. It is accompanied by fever, fatigue, weight loss, lymphadenopathy. and debilitation. The oral mucosa8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2 frequent findings include petechiae. edema, hemorrhages, and xerostomia. White hyper-keratotic lesions are rarely observed.The palate, lips, and buccal mucosa arc the most frequently involved sites.rhe oral manifestations of SI I are not pathognomonic.rhe differential diagnosis includes cicatricial Ebook Color atlas of oral diseases: Part 2 pemphigoid. erosive lichen planus, pemphigus, bullous pemphigoid, erythema multiforme. and der-maloinyosilis.l aboratory tests. Histopathologic and iEbook Color atlas of oral diseases: Part 2
nununo-lluorescent studies of biopsy specimens are essential to make the diagnosis, rhe presence of antidouble-stranded DNA antibodies in the scrum an8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2py consists of systemic steroids, nonsteroidal anti-inflammatory dnigs. antimalanals, immunosuppressants, and plasmapheresis if immune complexes are present.SclerodermaScleroderma is a chronic connective tissue disorder often classified as an autoimmune disease, although the precise cause is unknown Ebook Color atlas of oral diseases: Part 2. It primarily affects women between 30 and 40 years of age. I wo forms of the disease are distinguished: localized scleroderma (morphea) and progressEbook Color atlas of oral diseases: Part 2
ive systemic sclerosis. I he localized form has a favorable prognosis and involves the skin alone, whereas the systemic form of the disease is charact8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2in. hard, and inelastic, with a pale appearance. Skin necrosis and ulcer occur in severe cases (Fig.306). Involvement of the facial skin results in a characteristic facies with a small, sharp nose, expressionless stare, and narrow oral aperture (Fig. 307). Raynaud's phenomenon is usually present. Th Ebook Color atlas of oral diseases: Part 2e oral mucosa is pale and thin with ã smooth dorsal surface of the tongue due to papillary atrophy (Fig. 308). Frequent findings include smoothing outEbook Color atlas of oral diseases: Part 2
of the palatal folds, and short and hard tongue frenulum, which results in dysarthria. As the disease progresses, there arc limitations of mouth open8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli Ebook Color atlas of oral diseases: Part 2inosis cutis, Raynaud's phenomenon, esophageal dysfunction, sclerodac-tyly. and telangiectasia. Telangiectasia can occur on the lips and oral mucosa (Fig. 309).21. Autoimmune Diseases 191Fig. 306. Progressive systemic sclerosis, ulcer and gangrene of the sKIn and toe.Fig. 308. Progressive systemic s Ebook Color atlas of oral diseases: Part 2clerosis, pale and aUophic epithelium of the dorsum of the tongue1928821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cli8821. Autoimmune DiseasesDiscoid Lupus ErythematosusI .upus erythematosus is a chronic inflammatory autoimmune disease with a variable spectrum of cliGọi ngay
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