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Ebook Evidence-Based dermatology (3rd edition): Part 2

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Ebook Evidence-Based dermatology (3rd edition): Part 2

SECTION 3 Infective skin diseases, exanthems, and infestationsMasutaka Furue and Yuping Ran, editorsCHAPTER 38Local treatments for cutaneous wartsJupi

Ebook Evidence-Based dermatology (3rd edition): Part 2ing Chen’ and Yan Wu'' Department of Dcrautologv, Second Clink* *! Mcdkal Celege of Yangxbou University, Yary/bju. Chin** Department of Dcrautologv, N

o. 1 I lospital of Chin* Medical Unhwsit)C Shenyang, t hin*BackgroundDefinitionCutaneous waits are extremely common, benign, and usually selflimiting. Ebook Evidence-Based dermatology (3rd edition): Part 2

Infection of epidermal cells with the human papilloma virus (HPV) results in cell proliferation and a thickened, warty papule on the skin, lhe most c

Ebook Evidence-Based dermatology (3rd edition): Part 2

ommon sites involved are hands and feet, though any area of skin can also be infected. Genital watts are also common and frequently sexually transmitt

SECTION 3 Infective skin diseases, exanthems, and infestationsMasutaka Furue and Yuping Ran, editorsCHAPTER 38Local treatments for cutaneous wartsJupi

Ebook Evidence-Based dermatology (3rd edition): Part 2 rate varies according to different ages, populations, and periods of time, and It is the highest in children and young adults. 'Ị\»x> large populatio

n-based studies revealed prevalence rates of 0.84% and 12.9% 11,2). Studies in school populations showed rates of 12% in 4-6-ycar-olds and 24% in 16-1 Ebook Evidence-Based dermatology (3rd edition): Part 2

8 year-olds (3.4|.Etiology and risk factorsWarts are caused by HPV, of which there are over 70 different types, lesions are most common at sites of tr

Ebook Evidence-Based dermatology (3rd edition): Part 2

auma, and probably result from inoculation of virus into minimally damaged areas of epithelium. Plantar warts are often acquired from common bare-foot

SECTION 3 Infective skin diseases, exanthems, and infestationsMasutaka Furue and Yuping Ran, editorsCHAPTER 38Local treatments for cutaneous wartsJupi

Ebook Evidence-Based dermatology (3rd edition): Part 2mless and usually resolve spontaneously as a result of natural immunity within months or years. The rate of resolution is highly variable and probably

depends on a number of factors, including host immunity, age, HPV type, and site of infection. One frequently cited study of an institutionalized pop Ebook Evidence-Based dermatology (3rd edition): Part 2

ulation showed that two-thirds of warts resolved within a 2-year period [7]. Evaluation of clearance rates incontrol groups in randomized controlled t

Ebook Evidence-Based dermatology (3rd edition): Part 2

rials (RCTs) may also give some indication of natural clearance tendency, although a nonspecific benefit of vehicle bases may make interpretation diff

SECTION 3 Infective skin diseases, exanthems, and infestationsMasutaka Furue and Yuping Ran, editorsCHAPTER 38Local treatments for cutaneous wartsJupi

Ebook Evidence-Based dermatology (3rd edition): Part 2of 10 weeks (range 4-24 weeks).Diagnostic testsWarts are frequently diagnosed clinically. Microscopic examination obtained surgically can confirm the

diagnosis if there is doubt. HPV typing is used in research laboratories and occasionally in medicolegal cases to investigate child abuse.Aims of trea Ebook Evidence-Based dermatology (3rd edition): Part 2

tmentTo clear warts completely and permanently.Relevant outcomes•Cure rate (total clearance rate);•recurrence;•adverse reactions, such as pain and bli

Ebook Evidence-Based dermatology (3rd edition): Part 2

stering.Methods of searchData sources and search Strategy-All RCTs on the topkal treatments for extragenital warts were identified, without limitation

SECTION 3 Infective skin diseases, exanthems, and infestationsMasutaka Furue and Yuping Ran, editorsCHAPTER 38Local treatments for cutaneous wartsJupi

Ebook Evidence-Based dermatology (3rd edition): Part 2rence lists of prior reviews, systematic reviews, and trials were also checked The most recent searches were completed in June 2012.Study selection an

d data extractionTwo investigators independently screened studies for inclusion, retrieved potentially relevant studies, and determined eligible studi Ebook Evidence-Based dermatology (3rd edition): Part 2

es. Disagreements were resolved by consensus. Two investigators independently extracted data from the included studies usingEvidtnx bw-i Pmrninslrjji-

Ebook Evidence-Based dermatology (3rd edition): Part 2

. third Edition. Edited by Hywel G Williams. Mwhid Bigby Andrew Herrheimer. Imp Naldi. Berthold R/any. Robert I’. Dellivjlle, Yupeng Ran. and Masnlaka

SECTION 3 Infective skin diseases, exanthems, and infestationsMasutaka Furue and Yuping Ran, editorsCHAPTER 38Local treatments for cutaneous wartsJupi

Ebook Evidence-Based dermatology (3rd edition): Part 2e standardized forms and a third investigator was assigned with the checking process.Quality assessment

SECTION 3 Infective skin diseases, exanthems, and infestationsMasutaka Furue and Yuping Ran, editorsCHAPTER 38Local treatments for cutaneous wartsJupi

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