Ebook Ferri''s fast facts in dermatology: Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Ferri''s fast facts in dermatology: Part 2
Ebook Ferri''s fast facts in dermatology: Part 2
CHAPTER 3DISEASESAND DISORDERS1ACANTHOSIS NIGRICANS (AN)FIGURE 03-001. Velvety thickening of skin in flexural areas such as the axilla with brown-blac Ebook Ferri''s fast facts in dermatology: Part 2ck hyperpigmentation. Because of excess chafing, skin tags appear occasionally, as seen in this obese patient.FIGURE 03-002. Darkened, “dirty’ appearing thick skin with prominent lighter-colored deep skin lines. Several overlying warty or papillomatous growths are common in this condition.r 1 Genera Ebook Ferri''s fast facts in dermatology: Part 2l CommentsDefinition■Acanthosis nigricans reĩets to the presence of symmetrical brown velvety or verrucous plaques with a predilection for intertriginEbook Ferri''s fast facts in dermatology: Part 2
ous sites as the back of the neck, groin, and axillae (Fig. 03-001).Etiology■It is most commonly seen in obese individuals with insulin resistance or CHAPTER 3DISEASESAND DISORDERS1ACANTHOSIS NIGRICANS (AN)FIGURE 03-001. Velvety thickening of skin in flexural areas such as the axilla with brown-blac Ebook Ferri''s fast facts in dermatology: Part 2osisClinical Manifestation(s)■Asymptomatic. Ihe axilla and neck are the most commonly involved. In obese females who are hyperandrogenic, the vulva is the most commonly affected site.Physical Examination■ Symmetrical hyperpigmented velvety plaques of the major flexures (axilla, groin), neck (Fig. 03 Ebook Ferri''s fast facts in dermatology: Part 2-002), nipples, and vulva.42 Acne KeloidalisDiagnostic Tests■Laboratory evaluation often reveals elevated glucose levels. Additional useful laboratoryEbook Ferri''s fast facts in dermatology: Part 2
tests are thyroid-stimulating hormone (TSH) and follicle-stimulating hormone (FSH)Zluteinizing hormone (LH).DDx Differential Diagnosis■Seborrheic kerCHAPTER 3DISEASESAND DISORDERS1ACANTHOSIS NIGRICANS (AN)FIGURE 03-001. Velvety thickening of skin in flexural areas such as the axilla with brown-blac Ebook Ferri''s fast facts in dermatology: Part 2sisTreatmentFirst Line■Therapy for underlying cause (weight loss in obese, discontinuation of offending drugs, treatment ol malignancy il present)Second Line■Topical tretinoin, dermabrasion, ammonium lactate, carbon dioxide laserThird Line■Oral contraceptives, cyproheptadine, oral isotretinoin$3 Cli Ebook Ferri''s fast facts in dermatology: Part 2nical Pearl(s)■The sudden onset of acanthosis nigricans should be followed by investigation lor internal malignancy (c.g., upper endoscopy to rule outEbook Ferri''s fast facts in dermatology: Part 2
gastric cancer and computed tomography [CTj of abdomen and pelvis).■Skin changes precede the malignancy diagnosis (usually neoplasm of abdominal caviCHAPTER 3DISEASESAND DISORDERS1ACANTHOSIS NIGRICANS (AN)FIGURE 03-001. Velvety thickening of skin in flexural areas such as the axilla with brown-blac Ebook Ferri''s fast facts in dermatology: Part 2s).2ACNE KELOIDALISAGURE 03 003. A papular, pustular eruption found on the nape of the neck and often associated with keloidal scarring. A typical finding as seen here is the emergence of hair follicles from the center of the lesion. Ebook Ferri''s fast facts in dermatology: Part 2CHAPTER 3DISEASESAND DISORDERS1ACANTHOSIS NIGRICANS (AN)FIGURE 03-001. Velvety thickening of skin in flexural areas such as the axilla with brown-blacGọi ngay
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