Ebook HIV-associated hematological malignancies: Part 2
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Ebook HIV-associated hematological malignancies: Part 2
HIV-Associated Hodgkin Lymphoma9Marcus Hentrich, Michele spina, and Silvia MontotoContents9.1Introduction............................................. Ebook HIV-associated hematological malignancies: Part 2....................... 1209.2Epidemiology................................................................... 1209.2.1CD4 T-Cell Counts and Risk of HIV-HL.................................... 1219.3Pathology..................................................................... 1219.4Management........ Ebook HIV-associated hematological malignancies: Part 2............................................................ 1239.4.1Clinical Presentation and Diagnosis..................................... 1239.4.2Ebook HIV-associated hematological malignancies: Part 2
Prognostic Factors..................................................... 1249.4.3Primary Chemotherapy..................................................HIV-Associated Hodgkin Lymphoma9Marcus Hentrich, Michele spina, and Silvia MontotoContents9.1Introduction............................................. Ebook HIV-associated hematological malignancies: Part 2.............. 127References.......................................................................... 128M. Hentrich. MD (El)Department of Hematology and Oncology. Red Cross Hospital, University of Munich. Munich. Germanye-mail: marcus.hentrich@swmbrk.deM. SpinaDivision of Medical Oncology A. Natio Ebook HIV-associated hematological malignancies: Part 2nal Cancer Institute. Aviano. Italy e-mail: mspina@cro.ils. Montoto. MDCentre for Haemato-Oncology. St Bartholomew's Hospital. Barts Cancer Institute.Ebook HIV-associated hematological malignancies: Part 2
Queen Mary University of London. London, UKe-mail: s.montoto@qmul.ac.uk© Springer International Publishing Switzerland 2016119M. Hentrich. S.K. Barta HIV-Associated Hodgkin Lymphoma9Marcus Hentrich, Michele spina, and Silvia MontotoContents9.1Introduction............................................. Ebook HIV-associated hematological malignancies: Part 2f the most common non-AIDS-defining malignancies in patients infected with HIV. Unfavorable features such as higher frequency of advanced-stage disease and extranodal involvement are frequently encountered. Prior to the advent of combined antiretroviral therapy (cART). the prognosis of patients with Ebook HIV-associated hematological malignancies: Part 2 HIV-HL was poor. However, with standard curative-intent therapy and modern cART. the outcome is similar to that reported in the general population.9.Ebook HIV-associated hematological malignancies: Part 2
2EpidemiologyCompared with the general population, the incidence of H1V-HL is increased by approximately 10-15-fold with about 45-55 new cases per 100HIV-Associated Hodgkin Lymphoma9Marcus Hentrich, Michele spina, and Silvia MontotoContents9.1Introduction............................................. Ebook HIV-associated hematological malignancies: Part 2overview of recent studies providing data on standardized incidence ratios is given in Table 9.1.With a median age of 40-45 years, patients are about 10 years older than their HIV-negative counterparts. In high-prevalence areas such as South Africa. 61 % of HL cases were reported to be attributed to Ebook HIV-associated hematological malignancies: Part 2 HIV between 2007 and 2009 [11], while incidence rates in the USA arc highest among African Americans. A recent study on the prevalence of HIV infectiEbook HIV-associated hematological malignancies: Part 2
on among US Hodgkin lymphoma cases showed that between 2000 and 2010. 17 % of HL cases among African Americans were HIV related [12].Table 9.1 StudiesHIV-Associated Hodgkin Lymphoma9Marcus Hentrich, Michele spina, and Silvia MontotoContents9.1Introduction............................................. Ebook HIV-associated hematological malignancies: Part 2)Clifford 111USA1996-2002317.428 (AIDS only)9.4 13.2 (1996-2002)Biggar|2|France/ltaly1985-2005807410.8Serraino |3|HIV-Associated Hodgkin Lymphoma9Marcus Hentrich, Michele spina, and Silvia MontotoContents9.1Introduction.............................................Gọi ngay
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