Ebook Radiology of infectious diseases (Vol 2): Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Radiology of infectious diseases (Vol 2): Part 2
Ebook Radiology of infectious diseases (Vol 2): Part 2
Neonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2uscular rigidity and spasm caused by tetanospasmin, which is produced after Clostridium tetani (C. tetani) invade the navel.16.1Etiologyc. tetani is a rod-shaped Grain-positive bacillus, with a length of 2-18 pm and a width of 0.5-1.7 pm. It is strictly anaerobic, with surrounding flagella but no ca Ebook Radiology of infectious diseases (Vol 2): Part 2psule, c. tetani is characterized by forming wider round-shaped spore at the top of the thallus, producing a drumstick appearance microscopically. FilEbook Radiology of infectious diseases (Vol 2): Part 2
mlike spreading growth emerges after an incubation period of 24 h at 37 °C on blood plates, with accompanying p hemolysis. It performs neither carbohyNeonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2 role primarily by producing two types of exotoxins, tetanospasmin, and tetanolysin. Tetanospasmin is plasmid encoding. As a neurotoxin, it constitutes the major pathogenic substance to cause tetanus, with high affinity to brainstem nerve cells and the anterior horn cell nucleus of spinal cords. The Ebook Radiology of infectious diseases (Vol 2): Part 2 toxin can be absorbed by local never cells or travels along with lymph and blood flow to invade the central nerve system, with strong toxicity whichEbook Radiology of infectious diseases (Vol 2): Part 2
is just weaker than botulin. Chemically, it is a heatsensitive protein that can be dissolved at 65 °C for 30 min or be destructed by digestive proteinNeonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2ng the occurrence of tetanus remains elusive.Y. Guo (M)Department of Radiology. Taiping People’s Hospital.Daowai District. Harbin. Heilongjiang. Chinae-mail: guoyinglinhmu «>' I26.comL. Tang • B, LiuCT Department. The Second Affiliated Hospital.Harbin Medical University. Harbin. Heilongjiang. China1 Ebook Radiology of infectious diseases (Vol 2): Part 26.2Epidemiologyc tetani is ubiquitous in soil, dusts, and stool of animals anti humans. Neonatal tetanus occurs commonly when umbilical cord is cut duEbook Radiology of infectious diseases (Vol 2): Part 2
ring delivery, caused by invasion of c. tetani into the navel due to unsterilized or incompletely sterilized hands of midwives, scissors, or gauze.16.Neonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2livery, caused by invasion of c. tetani into the navel due to unsterilized or incompletely sterilized hands of midwives, scissors, or gauze and unawareness of the navel sterilization. The bandaging of navel provides an oxygen-insufficient environment facilitative to the reproduction of c. Mani. whic Ebook Radiology of infectious diseases (Vol 2): Part 2h consequently produce tetanotoxin. The tetanospasmin it produces travels along the nerve cord and lymph How into anterior horn cells of spinal cord aEbook Radiology of infectious diseases (Vol 2): Part 2
nd the brainstem motoneuron. Consequently, it binds to ganglioside in central nervous tissues. where it blocks the release of inhibitory neurotransmitNeonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2vous system is strengthened, causing sustained strong contraction of the muscles all over the body. The toxin can also excite sympathetic nerves, leading to tachycardia, hypertension, and profuse perspiration. Tetanolysin can cause necrosis of local tissues and impairments to the myocardium.16.4Clin Ebook Radiology of infectious diseases (Vol 2): Part 2ical Symptoms and SignsThe incubation period of neonatal tetanus commonly lasts for 3-14 days, and its occurrence is usually al 4th—7th day after deliEbook Radiology of infectious diseases (Vol 2): Part 2
ver)'. Therefore, it is commonly referred to asĨ) Springer Sciencc+Business Media Dordrecht and People's Medical Publishing House 2015H. Li (cd.). RadNeonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2ubation sustain more serious conditions and higher mortality rate. Clinically, the disease is divided into two types, mild type and serious type, rhe whole course of illness includes incubation periixl, pre-spasm stage, spasm Stage, and convalescent stage.The serious type of neonatal tetanus occurs Ebook Radiology of infectious diseases (Vol 2): Part 2within a week after delivery, rhe baby patients commonly experienced traditional mode of delivery, and the serious type generally has an incubation peEbook Radiology of infectious diseases (Vol 2): Part 2
riod of no more than 7 days, a pre-spasm Stage of no more than 24 h. a body temperature of no lower than 39 "C or a normal body temperature, spasm staNeonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2mild type of neonatal tetanus occurs after the first week of delivery, with an incubation period no shorter than 7 days, a pre-spasm stage no less than 24 h. trismus. spasms no longer than 10 s, and interval between spasms no less than 15 min.The period from the onset of symptoms to the initial conv Ebook Radiology of infectious diseases (Vol 2): Part 2ulsion is known as the pre-spasm stage. During the spasm stage, there are feeding refusal, trismus, facial muscular tension and pulled up mouth comersEbook Radiology of infectious diseases (Vol 2): Part 2
in appearance of forced smile, accompanying paroxysmal clenched fists, excessive flexion of upper extremities, and extension of lower extremities in Neonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2uced by slight stimulation. During the early stage with no obvious convulsion, the baby patients keep crying and the mouth fails to be wide open. The spatula test that touches the oropharynx with a spatula or tongue blade can cause an immediate trismus, which facilitates the diagnosis.16.5Neonatal T Ebook Radiology of infectious diseases (Vol 2): Part 2etanus-Related ComplicationsNeonatal tetanus can be complicated by many conditions, and the complications are commonly secondary to the serious type oEbook Radiology of infectious diseases (Vol 2): Part 2
f neonatal tetanus. Serious complications are the main cause of death in cases of neonatal tetanus. The baby patients sustain spasms anil increased seNeonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2hypoxia that further progress into encephaledema and cerebral hemorrhage. Due to the epi sixles of convulsion, lhe baby patients consume more energy and experience metabolic disturbance that lead to hypoglycemia and disturbances of electrolytes and aid base balance.Y.Guoetal.16.6Diagnostic Examinati Ebook Radiology of infectious diseases (Vol 2): Part 2ons16.6.1Laboratory Tests16.6.1.1Routine Blood TestIn the cases with secondary pulmonary infections, peripheral WBC count significantly increases.16.6Ebook Radiology of infectious diseases (Vol 2): Part 2
.1.2Bacteria CulturePyogenic aerobic bacteria can he isolated from secretions of wound, and c. tetani can also be isolated by anaerobic cul titre. As Neonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic mu Ebook Radiology of infectious diseases (Vol 2): Part 2fore, evidence from bacteria culture is not required for its diagnosis.16.6.2Diagnostic ImagingNeonatal TetanusYinglin Guo, Lili Tang, and Bailu Liu16Neonatal tetanus is an acute infectious disease characterized by trismus as well as systemic muGọi ngay
Chat zalo
Facebook