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Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

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Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram Singhhese glands develop irom endodermal lining of gut except parotid gland, which develops from ectodermal lining of the oral cavity. Ducts ol these gland

s open into different parts of the digestive tract. Although the spleen Is not a gland of the digestive tract but Is described here because of Its clo Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

se association with the diges tive tract. Note that the spleen develops between two layers of dorsal mesogastrlum.Salivary Glands̑here arc three pair

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

s of major salivary glands: (a) parorid, (h) submandibular, and (c) sublingual. 'iTicy arc so named because of their location. Secretion of these glan

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram SinghwThe liver, the largest gland in the body, develops from following three sources:1Parenchyma of the liver Is derived from endodermal hepatic bud of fo

regut2Fibrous stroma of the liver is derived from mesenchyme of septum transversum, a plate of Intraembryonlc mesoderm at the cranial edge of embryoni Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

c disc.3Sinusoids of liver develop from absorbed and broken vitelline and umbilical veins within the septum transversum.The liver develops from an end

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

odermal hepatic bud that arises from ventral aspect of rhe discal part of foregut, just ar Its junction With the midgut (Fig. 14.1).The hepatic bud gr

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram Singhtica and a small caudal part called pars cystica. The pars hqxiticu forms (he liver, while purs cystica forms the gallbladder and cystic duct. The par

t vl bud proximal to pars cystica forms common bile duct (CBD).The pars hepalica lurcher divides into right and lelt portions that form right and left Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

lobes ol the liver respectively. Initially both lobes ol the liver are of equal size.As the right and lell portions of the pars hepalica enlarge, the

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

y extend into rhe septum rransversum. The cells arising from them form interlacing hepatic cords or cords of hepatocytes. In this process, vitelline a

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram Singhater become radially arranged in hejxiric lobules. The bile canaliculi and ductules arc formed in liver parenchyma and establish connections with exrr

aheparic bile ducts secondarily ar a Liter stage (Fig. 14.3). Due to rapid enLirgemenl, liver occupies major portion ol the abdominal cavity forcing t Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

he coils ol the gut to herniate through umbilicus (physiological hernia). The oxygen-rich blood supply and proliferation ol hemopoietic tissue are res

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

ponsible for the massive enlargement ol the liver.Adult derivatives of various components ol liver from embryonic structures are given in Table 14.1.N

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram Singhne life (IUL) and continue till birth. Later, the hemopoietic function of the liver Is taken over by the spleen and bone marrow.•The hepatocytes start

secreting bile at about twelfth week (3 months) of IUL. The bile enters intestine and imparts a dark green color to first stools (meconium) passed by Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

newborn.r Clinical Correlation 1Congenital anomalies of the liver1Riedel’s lobe: It is a tongue-like extension from the right lobe of the liver (Fig

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

144) It develops as an extension of normal hepatic tissue from the inferior margin of the right lobe of the liver.2Polycystic disease of the liver: Th

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh liver. A. Hepatic bud arising Imrn lon-gul at its junction with the midgut. R. Growth OÍ hepatic bud towards septum transversum through ventral mesng

astrium. Note the subdivision ol hepatic hud mtn pars hcpâtica and pars cystica, c. Division of pars hcparica into right and left portions. D. Fully f Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

ormed liver and gallbladder along with their ducts.Fig. 14.2 Umbilical and vitelline veins passing through the septum transversum to enter the sinus v

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

enosus.them with the extrahepatic btle ducts. Failure of union of some of these ducts may cause the formation of cysts within the liver. The polycysti

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram Singhahepatic biliary atresia cannot be subjected to surgical correction As a result, there are only two options for parents:(a)to go for Irver transplant

of the child or (b) to let the child die.4Caroli's disease: It is characterized by congenital dilatation of intrahepatic Miary tree, which may lead to Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

the formation of sepsis, stone, and even carcinoma5Others: They include rudimentaiy liver, absence of quadrate lobe and presence of accessory liver t

Ebook Textbook of clinical embryology : Part 2 - Vishram Singh

issue in the falciform Ilgam ent.160Textbook of Clinical EmbryologyFig. 14.3 Histological components lit developing liver. A. Arrangement <>t Itepalii

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

Ebook Textbook of clinical embryology : Part 2 - Vishram Singhinusoids (derivatives of vitelline and umbilical veins), and hemopoietic tissue (derivative of septum transversum).B

Major Digestive Glandsand SpleenOverviewThe major glands associated with digestive (alimentary) tract are salivary glands, liver, and pancreas. All th

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