DNA Microarrays (Gene Chips) and Cancer
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DNA Microarrays (Gene Chips) and Cancer
Cancer Education ProjectDNA Microarrays (Gene Chips) and CancerOverview:This series of activities explores the use of DNA Microarray (Gene Chips) tech DNA Microarrays (Gene Chips) and Cancerhnology in investigations to understand the role of genes involved in causing cancer. It also illustrates how the results of these investigations can be applied to diagnosing and treating cancer patients.Overview of Microarray Activities (‘Note: Part 3 may be done for homework)•Part 1: Gene Expressi DNA Microarrays (Gene Chips) and Canceron and Cancer (40 minutes)Students view a PowerPoint presentation that illustrates and helps them understand the concepts of gene expression and canceDNA Microarrays (Gene Chips) and Cancer
r as a change in gene expression. This PowerPoint is followed by a reading activity that introduces students to the concepts of cancer genes and diffeCancer Education ProjectDNA Microarrays (Gene Chips) and CancerOverview:This series of activities explores the use of DNA Microarray (Gene Chips) tech DNA Microarrays (Gene Chips) and Cancergenes would lead to cancer.•Part 2: DNA Microarray Technology (40 minutes)Students are introduced to microarray technology through a PowerPoint and a simulated paper microarray activity. They analyze the microarray results to compare gene expression in normal and cancerous cells.•Part 3: Apply Your DNA Microarrays (Gene Chips) and CancerUnderstanding of Microarray Technology (20 minutes)*This worksheet reviews concepts of microarray technology and allows students to apply these concepDNA Microarrays (Gene Chips) and Cancer
ts to analyze how a cancer drug affects gene expression.•Part 4: Personalized Medicine (40 minutes)Students read about a new microarray test that makeCancer Education ProjectDNA Microarrays (Gene Chips) and CancerOverview:This series of activities explores the use of DNA Microarray (Gene Chips) tech DNA Microarrays (Gene Chips) and Cancerarning Center - Cancer Education ProjectCopyright ® 2CO7. University of RochesterMary De copied for Classroom use1Microarrays and Cancer•Part 5: Microarrays and Personalized Medicine (60 minutes)This simulated microarray “wet lab’ illustrates how personalized medicine could be used to select breast DNA Microarrays (Gene Chips) and Cancercancer patients who are likely to need chemotherapy. Students prepare a microarray and analyze the results to determine which patients might benefit mDNA Microarrays (Gene Chips) and Cancer
ost from chemotherapy.•Part 6: Microarrays and Cancer Diagnosis (20 minutes)This data analysis activity illustrates how microarrays can be used in canCancer Education ProjectDNA Microarrays (Gene Chips) and CancerOverview:This series of activities explores the use of DNA Microarray (Gene Chips) tech DNA Microarrays (Gene Chips) and Canceron for the production of proteins.•When a gene is transcribed in a cell, the coded information In the gene is copied to produce messenger RNA (mRNA)•The coded information in messenger RNA Is then translated to produce a protein.•"Gene Expression” refers to the processes by which a gene IS transcribe DNA Microarrays (Gene Chips) and Cancerd and translated to produce a functional protein.•All cells in an organism contain the same genes, but different genes are expressed (transcribed or "DNA Microarrays (Gene Chips) and Cancer
turned on”) In different cells under different conditions. This IS also known as "differential gene expression."•Differential gene expression results Cancer Education ProjectDNA Microarrays (Gene Chips) and CancerOverview:This series of activities explores the use of DNA Microarray (Gene Chips) tech DNA Microarrays (Gene Chips) and Cancerto different environmental conditions.•Cell structures and functions may change when gene expression is turned on. off. increased or decreased.•Cancer can develop when gene mutations lead to changes in genes or gene expression that disrupt the regulation of cell division.•DNA microarrays (gene chips DNA Microarrays (Gene Chips) and Cancer) are a new technology that scientists use to measure the expression of thousands of genes at one time.•Microarrays illustrate important connections bDNA Microarrays (Gene Chips) and Cancer
etween genetics (genes, DNA. RNA, and proteins) and cancer.•Microarrays technology has uses in many areas of biology and medicine.Citations:•Parts 1 aCancer Education ProjectDNA Microarrays (Gene Chips) and CancerOverview:This series of activities explores the use of DNA Microarray (Gene Chips) techCancer Education ProjectDNA Microarrays (Gene Chips) and CancerOverview:This series of activities explores the use of DNA Microarray (Gene Chips) techGọi ngay
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