NHI KHOA TỔN THƯƠNG GAN CẤP
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: NHI KHOA TỔN THƯƠNG GAN CẤP
NHI KHOA TỔN THƯƠNG GAN CẤP
Acetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, Executive NHI KHOA TỔN THƯƠNG GAN CẤP Director, and Rebecca Jerome, MLIS, MPH, Manager, Translational ResearchVanderbilt Institute for Clinical and Translational ResearchVanderbilt University Medical Center, Nashville Tennessee, USA(see Appendix 1 fora list of additional contributors)Submission Date: November 30, 2020PROJECT Repurposin NHI KHOA TỔN THƯƠNG GAN CẤPg EssentialR E M E D I MEDicines InternationallyMAKE BETTER USE OF MEDICINES WE ALREADY HAVEProject I Remedi aims to uncover new therapeutic uses forNHI KHOA TỔN THƯƠNG GAN CẤP
hundreds of medicines on the Essential Medicines List, seek approval to add them to the EML. and amplify availability of new uses to benefit priority Acetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, Executive NHI KHOA TỔN THƯƠNG GAN CẤPtment and focal point (if applicable).3Name of organization(s) consulted and/or supporting the application...............................64International Nonproprietary Name (INN) and Anatomical Therapeutic Chemical (ATC) code of themedicine............................................................ NHI KHOA TỔN THƯƠNG GAN CẤP..................................65Dose forms(s) and strength(s) proposed for inclusion..............................................66Whether listinNHI KHOA TỔN THƯƠNG GAN CẤP
g is requested as an individual medicine or as representative of a pharmacological class. ...67Treatment details (requirements for diagnosis, treatmenAcetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, Executive NHI KHOA TỔN THƯƠNG GAN CẤPw of benefits: summary of evidence of comparative effectiveness..............................9Identification of clinical evidence (search strategy, systematic reviews identified, reasons for selection/exclusion of particular data).............................................................9Summary NHI KHOA TỔN THƯƠNG GAN CẤPof available data (appraisal of quality, outcome measures, summary of results)..............9Summary of available estimates of comparative effectiveneNHI KHOA TỔN THƯƠNG GAN CẤP
ss........................................1210Review of harms and toxicity: summary of evidence of safety.....................................12EstimaAcetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, Executive NHI KHOA TỔN THƯƠNG GAN CẤPin non-acetaminophen induced acute liver failure:...........................................................................................12Description of the adverse effects/reactions and estimates of their frequency (drawn from the broader NAC literature on human use)............................ NHI KHOA TỔN THƯƠNG GAN CẤP...........................................12Summary of available data..........................................................................13IdenNHI KHOA TỔN THƯƠNG GAN CẤP
tification of variation in safety that may relate to health systems and patient factors........1511Summary of available data on comparative cost and cAcetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, Executive NHI KHOA TỔN THƯƠNG GAN CẤPvailability of pharmacopoeia! standards (British Pharmacopoeia, International Pharmacopoeia, UnitedStates Pharmacopoeia, European Pharmacopeia). Summary of available data on comparative cost and costeffectiveness of the medicine........................................................................ NHI KHOA TỔN THƯƠNG GAN CẤP17Literature summaries: non-acetaminophen acute liver failure, organized by precipitating exposure/condition..........................................NHI KHOA TỔN THƯƠNG GAN CẤP
.........................................18LITERATURE SUMMARY: Evidence describing use of NAC in general non-acetaminophen-induced acute liver injury.Acetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, Executive NHI KHOA TỔN THƯƠNG GAN CẤPke-associated acute liver injury.....24LITERATURE SUMMARY: Evidence describing use of NAC in alcohol poisoning-associated acute liver injury .............................................................................................. ...25LITERATURE SUMMARY: Evidence describing use of NAC in mush NHI KHOA TỔN THƯƠNG GAN CẤProom toxin-induced acute liver injury..252Acetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, Executive Acetylcysteine (N-acetylcysteine, NAC) for the management of non-acetaminophen-induced acute liver failureSubmitted by:Jill M. Pulley, MBA, ExecutiveGọi ngay
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