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Discovery of novel small molecule for treatment of neuropathic pain

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Nội dung chi tiết: Discovery of novel small molecule for treatment of neuropathic pain

Discovery of novel small molecule for treatment of neuropathic pain

§ Í8 LDiscovery of Novel Small Molecule for Treatment of Neuropathic PainA dissertation submitted to the Graduate School of Innovative Life Science,Un

Discovery of novel small molecule for treatment of neuropathic pain niversity of ToyamaToyama, Japanfor the degree ofDOCTORATE OF PHILOSOPHY (Ph.D.)in .Advanced Nanosciences and Bioscicnccs43525ByNGUYEN HUY DUContentsA

bbreviation..................................................................3Introduction............................................................ Discovery of novel small molecule for treatment of neuropathic pain

......4Chapter. 1 Recognizing prenyl flavanones as novel T-type calcium channel blockers useful for paintherapy.......................................

Discovery of novel small molecule for treatment of neuropathic pain

........................131.1.Introduction...........................................................131.2.Results....................................

§ Í8 LDiscovery of Novel Small Molecule for Treatment of Neuropathic PainA dissertation submitted to the Graduate School of Innovative Life Science,Un

Discovery of novel small molecule for treatment of neuropathic pain ................................24Chapter.2 Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin........................

.....................................252.1.Introduction...........................................................252.2.Results....................... Discovery of novel small molecule for treatment of neuropathic pain

.........................................252.3.Discussion.............................................................292.4.Conclusion................

Discovery of novel small molecule for treatment of neuropathic pain

.............................................31Chapter.3 T-type calciumchannel blockers as anti-hyperalgesic agents againstbortezomib-induced peripher

§ Í8 LDiscovery of Novel Small Molecule for Treatment of Neuropathic PainA dissertation submitted to the Graduate School of Innovative Life Science,Un

Discovery of novel small molecule for treatment of neuropathic pain ........................................................333.3.Discussion.............................................................373.4.Conclusion.

............................................................39Conclusion...................................................................40Acknowled Discovery of novel small molecule for treatment of neuropathic pain

gment...............................................................41Experimental section.........................................................42E

Discovery of novel small molecule for treatment of neuropathic pain

xperiment of chapter. 1.....................................................42Supplementary of chapter. 1.............................................

§ Í8 LDiscovery of Novel Small Molecule for Treatment of Neuropathic PainA dissertation submitted to the Graduate School of Innovative Life Science,Un

§ Í8 LDiscovery of Novel Small Molecule for Treatment of Neuropathic PainA dissertation submitted to the Graduate School of Innovative Life Science,Un

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