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Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

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Nội dung chi tiết: Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata lITYFINAL REPORTBACHELOR GRADUATIONBy Tô Hiền MinhProject:Antibacterial activity on multidrug resistance bacteria Stenotrophomonas maltophilia (strain

K279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator Pteris vittata L.Supervisor: Dr. NGUYỀN THỊ KIÊU OANHUnivers Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

ity of Science and Technology of HanoiHanoi, November 2020AcknowledgementsForemost. I would like to express my deepest gratitude to my supervisors Dr.

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

Nguyền Thị Kiều Oanh and PhD student Nguyền Ngọc Liên from Life Sciences Department for their countless support, encouragement and guidance throughou

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata lithout the opportunity that they give me to join the project and fulfill my bachelor thesis.Besides. I want to thank all of the other professors and l

ecturers in the Life Science Department who always inspire us with their enthusiasm and passion for science - the best role models for US to become in Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

the future. Moreover. I'm sincerely proud to spend my most wonderfill 3 years of education with all of my friends in the PMAB class of 2020. We have

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

always tried hard and inspired each other to break our own limits. Especially Phạm Anil Thư and Trần Phương Trang for always supporting and motivating

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata lstrategy.Most importantly, all of my thankfulness goes to my family and loved ones, they have nurtured and educated me to become who I am today, who i

s not afraid to learn and always grateful for what is coming ill the futureList of Abbreviationsp. vittata s. maltoph ilia TMP-SMX MRSA MDR FDA ROS ES Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

BL UPLC-QqQ-MSPieris vittata L. Stenotrophomonas maltopilia trimethoprim- sulfamethoxazole Methicillin-resistant Staphylococcus aureus Multidrug resis

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

tant Food and Drug Administration Reactive oxygen species Extended spectrum betalactamase Ultra Performance Liquid Chromatography coupled triple quadr

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata lre regression- Discrimination analysis Tryptone soya broth Dimethyl sulfoxide Colony forming unit Gentamicin Group promoting Group InhibitingList of F

igures and TablesFiguresFigure 1 Microdilution testing of p. vittata root and leave extract on the growth curve of s. maìĩophilia strain K279aFigure 2 Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

. The inhibition percentage of p vittata leave and roots extracts on the growth of s. maìĩophilia strain K279aFigure 3. Correlation circles of PLS reg

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

ression between metabolites content (M) and the inhibition percentage of s. maltoph iìia K279a growth by leave and root extracts (Y)TablesTable I. Pai

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l linear correlation betweenmetabolite intensity (XI) and antibacterial activity of leave or root extracts (X2).Abstract:Pieris vittata L. is a heavy m

etal hyperaccumulator plant abundant in Thai Nguyen mining ore of Vietnam, which can change its secondary metabolic profile for environmental adaptati Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

on, leading to the shift of its synergistic bacterial system. Under the same heavy metal stress, multidrug resistance bacteria can express intrinsic e

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

fflux pumps for both metal and antibiotics extrudation Investigation on p. vittata bioactivity IS a potential approach in finding novel antimicrobial

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata lstic nosocomial pathogen which can cause severe respừatory tract infection. Microdilution testing shows that p. vittata roots and leave extracts have

either antibacterial activity or growth promoting activity on the strain. In our study, the first time metabolic profile of p. vittata identified by a Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

UPLC-QqQ-MS was statistically predicted for Its correlation with antibacterial activity. Flavonoid compounds such as pelargonin, quercetin were predi

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata l

cted to act against the s. maỉtophiỉia and some alkaloids show its growth stimulator role. These results bring out new directions to develop antibacte

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

Antibacterial activity on multidrug resistance bacteria stenotrophomonas maltophilia (strain k279a) and its correlation to secondary metabolic profile of heavy metal hyperaccumulator pteris vittata leris vittata. Stenotrophonionas maltophilia, antibacterial activity, bacterial growth promoting, secondary metabolites. PLS regression model.

UNIVERSITY OF SCIENCE AND TECHNOLOGY OF HANOI UNIVERSITY DES SCIENCES ET DES TECHNOLOGIES DE HANOIUNDERGRADUATE SCHOOLTothI7/Í7 V4 w IRA \'CE UNIVERSI

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