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Ebook BRS Physiology (6th edition): Phần 2

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Nội dung chi tiết: Ebook BRS Physiology (6th edition): Phần 2

Ebook BRS Physiology (6th edition): Phần 2

Renal and Acid-Base PhysiologyI. BODY FLUIDSTotal body water (TBW) Is approximately 60% of body weight.The percentage of TBW is highest in newborns an

Ebook BRS Physiology (6th edition): Phần 2nd adult males and lowest in adult females and in adults with a large amount of adipose tissue.A.Distribution of water (Figure 5.1 and Table 5.1)1Intr

acellular fluid (ICF)E is two-thirds of TBW.The major cations of ICF are K* and Mg2‘.The major anions of ICF are protein and organic phosphates (adeno Ebook BRS Physiology (6th edition): Phần 2

sine triphosphate IATPL adenosine diphosphate IADP], and adenosine monophosphate lAMPl).2Extracellular fluid (ECF)■ is one-third of TBW.is composed of

Ebook BRS Physiology (6th edition): Phần 2

interstitial fluid and plasma. The major cation of ECF is Na*.H The major anions of ECF are Cl- and HCO/.a.Plasma is one-fourth of the ECF.Thus, it i

Renal and Acid-Base PhysiologyI. BODY FLUIDSTotal body water (TBW) Is approximately 60% of body weight.The percentage of TBW is highest in newborns an

Ebook BRS Physiology (6th edition): Phần 2fourth ofTBW (3/4 X 1/3).The composition of interstitial fluid is the same as that of plasma except that it has little protein. Thus, interstitial flu

id is an ultrafiltrate of plasma.360-40-20 ruleTBW is 60% of body weight.K ICF is 40% of body weight.ECF is 20% of body weight.B.Measuring the volumes Ebook BRS Physiology (6th edition): Phần 2

of the fluid compartments (see Table 5.1)1Dilution methoda.A known amount of a substance is given whose volume of distribution is the body fluid comp

Ebook BRS Physiology (6th edition): Phần 2

artment of interest.E For example:-1Tritiated water is a marker for TBW that distributes wherever water Is found.-2Mannitol Is a marker for ECF becaus

Renal and Acid-Base PhysiologyI. BODY FLUIDSTotal body water (TBW) Is approximately 60% of body weight.The percentage of TBW is highest in newborns an

Ebook BRS Physiology (6th edition): Phần 2is a dye that binds to serum albumin and is therefore confined to the plasma compartment.147148 BRS PhysiologyFIGURE 5.1 Body fluid compartments.b.The

substance is allowed to equilibrate.c.The concentration of the substance is measured in plasma, and the volume of distribution is calculated as follo Ebook BRS Physiology (6th edition): Phần 2

ws:„ .____ AmountVolume = —----—-—7-—Concentrationwhere:

Renal and Acid-Base PhysiologyI. BODY FLUIDSTotal body water (TBW) Is approximately 60% of body weight.The percentage of TBW is highest in newborns an

Renal and Acid-Base PhysiologyI. BODY FLUIDSTotal body water (TBW) Is approximately 60% of body weight.The percentage of TBW is highest in newborns an

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