Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
UNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2emic heart disease (IHD) is the single most common cause of death in developed nations as well as in many developing countries [1.2]. IHD IS an umbrella term that encompasses a spectrum of catdiac disorders caused by myocatdial ischemia. The notable examples of IHD include stable IHD (SIHD) (with st Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2able angina as its prototypical manifestation) and acute coronary syndromes (ACS), among many others This chapter provides an overview of 1HD and discEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
usses the pathophysiology of SIHD and the mechanistically based drug targeting of stable angina. Chapter 14 reviews antiangi-nal drugs that have alreaUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2ples and guidelines regarding the management of SIHD/stable angina in clinical practice are given in Chapter 15.13.2CLASSIFICATION. EPIDEMIOLOGY.AND PATHOPHYSIOLOGY13.2.1 Classification/3.2././ Definition of I HI) and the International Statistical Classification of Diseases and Related Health Proble Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2ms-lOth Revision Classification As noted earlier, the term IHI) refers to a spectrum of diseases of the heart caused by decreased oxygen supply to theEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
myocardium. I'bc International Statistical Classification of Diseases and Related Health Problems-10th Revision (ICD-10) classifiesHID into the folloUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2 current complications following acute myocardial infarction4Subsequent myocardial infarction5Other acute IHD6Chronic 1HD including coronary artery disease (CAD), among others13.2.1.2 Conventional Classification of I HD ICD-10 classification of HID is comprehensive and authoritative: however, it is Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2complicated and often limes causes confusion. Hence, a simplified classification scheme is frequently used to divide IHI) into two general categoriesEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
(Fig. 13.1): (1) SIHD with stable angina as the prototypical manifestation and (2) ACS that include unstable angina. non-ST-clcvation myocardial infarUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2nomenclature, stable angina is the chief manifestation of SIHD or SCAD. Indeed, the main symp tomalic clinical presentations of SIIID include (i) classical chronic stable angina caused by epicardial stenosis: (ii) angina caused by microvascular dysfunction (also known as microvascular angina), (iii) Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2 angina caused hy vasospasm (vasospastic angina), and (iv) symptomatic ischemic cardiomyopathy [3].Cardiovascular fowuu-s: From Motrrutor ptwmoiotrifyEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
IO EvidMre-BaredThrraprulirt, First Edition. Y. Robert l.i. © 201 s John Wiley A Sons. Inc. Published 201$ by John Wiley & Softs. Inc.246 OVERVIEW OFUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2 and disease description120: Angina pectoris120.0. Unstable angina Angina: •Crescendo •IX.- novo effort •Worsening effort Intermediate coronary syndrome Preinfarction syndrome 120.1. Angina pectoris with documented spasm Angina: •Angiospastic •Prinzmetal •Spasm induced •Variant 120.8. Otlrer forms o Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2f angina pectoris Angina of effort Stenocardia 120 9. Angina pectoris, unspecified Angina: •NOS •Cardiac Anginal syndrome Ischemic chest pain121: AcutEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
e myocardial infarction121.0. Acute transmural myocardial infarction of anterior wall Transmural infarction (acute) (of): •Anterior (wall) NOS •AnteroUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2all •Inferior (wall) NOS •Inferolateral •Inferoposterior 121.2.Acute transmural myocardial infarction of other sites Transmural infarction (acute) (of): •Apical-lateral •Basal-lateral •High lateral •Lateral (wall) NOS •Posterior (true) •Posterobasal •Posterolateral •Posteroseptal •Septal NOS 121.3.A Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2cute transmural myocardial infarction of unspecified site Transmural myocardial infarction NOS 121.4.Acute subendocardial myocardial infarction NoniraEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
nstnural myocardial infarction NOS 121.9. Acute myocardial infarction, unspecified Myocardial infarction (acute) NOS122: Subsequent myocardial infarctUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2eroseptalCLASSIFICATION. EPIDEMIOLOGY. AND PATHOPHYSIOLOGY 247TABLE 13.1 (Continued)ICD-lOcodcICD-10 subcode and disease description122.1 .Subsequent myocardial infarction of inferior wall Subsequent infarction (acute) (of): •Diaphragmatic wall •Inferior (wall) NOS •Inferolateral •Inferoposterior 12 Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 22.8.Subsequent myocardial infarction of other sites Subsequent myocardial infarction (acute) (of): •Apical-lateral •Basal-lateral •High lateral •LaterEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
al (wall) NOS •Posterior (true) •Posterobasal •Posterolateral •Posteroseptal •Septal NOS 122.9.Subsequent myocardial infarction of unspecified site123UNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2(121-122) •Not specified as current complications following acute myocardial infarction (13 L-. I5I.-F'123.0. Hemoperieaidium as current complication follow ing acute myocardial infarction 123.1 Atrial septal defect as current complication following acute myocardial infarction 123.2.Ventricular sept Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2al defect as current complication following acute myocardial infarction 123.3.Rupture of cardiac wall w ithout hemopeiicardium as current complicationEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
following acute myocardial infarction Excl.' w ith hemopericardium (123.0) 123.4.Rupture of chordae lendincac as current complication follow ing acutUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2m, auricular appendage, and ventricle as current complications following acute myocardial infarction 123.8 Other current complications following acute myocardial infarction124: Otlrer acute ischemic heart diseases Excl.: angina pectoris (120.-). transient myocardial ischemia of newborn (P29.4X124.0. Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2 Coronary thrombosis not resulting in myocardial infarction Coronary (artcryXvcin): •Embolism •Occlusion •Thromboembolism Excl.: specified as chronicEbook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2
or with a stated duration of >4 weeks (>28 days) from onset (125.8) 124.1 Dressier syndrome Post myocardial infarction syndrome 124.8 Other forms of aUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIsche Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2 NOS (125.9)125: Chronic ischemic heart disease Excl.: cardiovascular disease NOS (15I.6X125.0. Atlieroscleiolic cardiovascular disease, so described 125.1 Atherosclerotic heart disease Coronary (artery): •Atheroma •Atherosclerosis •Disease •Sclerosis(Continued)248 OVERVIEW OF ISCHEMIC HEART DISEASE Ebook Cardiovascular diseases - From molecular pharmacology to evidence-Based therapeutics: Part 2. STABLE ANGINA. AND DRUG THERAPYUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIscheUNIT IVISCHEMIC HEART DISEASE: STABLE ISCHEMIC HEART DISEASE13OVERVIEW OF ISCHEMIC HEART DISEASE, STABLE ANGINA, AND DRUG THERAPY13.1INTRODUCTIONIscheGọi ngay
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