Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
SECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythemat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2tosus, are important indicators of severe underlying systemic disease and rare conditions, such as acanthosis nigricans, can be markers of internal malignancy. Pemphigus vulgaris is potentially lethal, as is HIV infection - which can give rise to a variety of mucosal lesions. Biopsy is mandatory, pa Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2rticularly in the bullous diseases as. in such cases, the diagnosis can only be confirmed by microscopy. In other cases, microscopic findings can be lEbook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
ess definite, but often (as in the case of major aphthae for example) serve to exclude more dangerous diseases. Mucosal ulceration - a break in epitheSECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythemat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2sal diseases as discussed below.PRIMARY HERPETIC STOMATITIS -> Summary p. 221Primary infection is caused by Herpes simplex virus, usually type I. which, in the non-immune, can cause an acute vesicu-lating stomatitis. However, most primary infections are sub-clinical. Thereafter, recurrent (reactivat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2ion) infections usually take the form of herpes labial is (cold sores or fever blisters).Transmission of herpes is by close contact and up to 90% of iEbook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
nhabitants of large, poor, urban communities, develop antibodies to herpes virus during early childhood. In many British and US cities, by contrast, aSECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythemat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2has declined and It is seen in adolescents or adults, rather than children. It is more common in the immunocompromised, such as HIV infection, when It can be persistent or recurrent.Clinical featuresThe early lesions arc vesicles which can affect any part of the oral mucosa, but the hard palate and Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2dorsum of the tongue arc favoured sites (Figs 12.1 and 12.2). The vesicles arc domeshaped and usually 2-3 mm in diameter. Rupture of vesicles leaves cEbook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
ircular, sharply defined, sliallow ulcers with yellowish or greyish floors and red margins. The ulcers are painful and may interfere with eating.The gSECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythemat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2nd systemic upset, sometimes severe, particularly in adults.Table 12.1Important CJUSM Ct oral mucosal uk*rsVosicuto bullous dEioawslaceration without preceding vcsiculationInfectivePrimary herpetfc stomatitis Herpes labalis Herpes zoster am cbfelcenpox Hand-fcot-end-moixh diseaseCylcrregỂíơ.tus-asso Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2ớated Licera&on Soma aojte spesrtc fevers Tuberculosis Syphtts206Ncn-rilectoePerifchflus '.ưạarts Mucousmembra ie pemphi^od Lnaar Iryx dsease DermatitEbook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
is herpetiformis Billows erythema mjbfomieTraumatic Aphthous stomatitis Behcet's ctoea.se HM-assocHted mixxxsai ucers Lichen planus Lupus erytharratosSECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythemat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2Pale veactes and Ubers are vtab'e co tha pÊtóte and gingvae. eepetíaiy aiterkxty. ard the gingi/ae are erytterra-ious and szoten.Fig. 12.2 Hwpetic stomatitis. A group Ct recently repined vestóes co tr»e hard palate, a chariKtenstc site. Tha indwtua) tesKos are of ramarkatty urrtcon size txit several Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2 have ccetesced Io term larger rregjtr ulcersOral lesions usually resolve within a week to ten days, but malaise can persist so long that an adult mayEbook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
not recover fully for several weeks.PathologyVesicles are sharply defined and form in (he upper epithelium (Fig. 12.3). Virus-damaged epithelial cellSECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythemat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2(Fig. 12.4). Incomplete division leads to formation of multinucleatcd cells. Later, the full thickness of the epithchum is destroyed to produce a sharply defined ulcer (Fig. 12.5).DiagnosisThe clinical picture is usually distinctive (Box 12.1). A smear showing virus-damaged cells is additional diagn Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2ostic evidence. A rising titre of antibodies reaching a peak after 2-3 weeks provides absolute but retrospective confirmation of (he diagnosis.DISEASEEbook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
S of the oral mucosa. NTRÙUUC I wrr wSECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythemat Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2ide Slid.ow*nn12Fig. 12.4 A smear (rem a herpetic vesicle. The deterded degeré-atrvg rate of the epthdd cels cluster together to gr.-e the typical muterry appearance.TreatmentAciclovir is a potent antiherpetic drug and is life-saving for potentially lethal herpetic encephalitis or disseminated infec Ebook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2tion. Aciclovir suspension used as a rinse and then swallowed should accelerate healing of severe herpetic stomatitis if used sufficiently early. BedEbook Cawson’s essentials of oral pathology and oral medicine (8/E): Part 2
rest, fluids and a soft diet may sometimes be required.207SECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythematSECTION2SOFT TISSUE DISEASE205CHAPTER12Diseases of the oral mucosa: introduction and mucosal infectionsA few mucosal diseases, such as lupus erythematGọi ngay
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