Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2
Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2
Metabolism of Steroids11and Other LipidsCONTENTSSTEROID METABOLISMCholesterol Synthesis&IC AcdsPHOSPHOGLYCERIDE METABOLISMSynthesis of Simple Phosphog Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2glycendesComplex PhospholipidsPhospholipasesRESPIRATORY DISTRESS SYNDROMESPHINGOLIPID METABOLISMCeramide SynthesisABO Blood GroupsSphingolipidoses (Lipid Storage Diseases)EICOSANOIDSProstaglandinsThromboxanesLeukotrienesCholesterol SynthesisCholesterol is synthesized in four phases, all of which are Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2 in the cytoplasm. First, the precursor mevalonate is synthesized, followed by its conversion to an isoprenoid (5 Carbons) intermediate. Then the isopEbook Elsevier''s integrated review biochemistry (2nd edition): Part 2
renoid intermediate is polymerized into a 30-carbon steroid carbon skeleton, squalene. The final phase consists of cyclizing and refining the 30-carboMetabolism of Steroids11and Other LipidsCONTENTSSTEROID METABOLISMCholesterol Synthesis&IC AcdsPHOSPHOGLYCERIDE METABOLISMSynthesis of Simple Phosphog Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2sis steps in this pathway.Six-Carbon MevalonateThree reactions synthesize 6-carbon mevalonate by condensation of 3 molecules of acetyl-CoA (Fig. 11-2).•• STEROID METABOLISMCholesterol is the most ubiquitous and abundant steroid found in human tissue. It serves as a nucleus for the synthesis of all s Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2teroid hormones and bile adds. The major location for the synthesis of cholesterol is the liver, although it is synthesized in significant amounts inEbook Elsevier''s integrated review biochemistry (2nd edition): Part 2
intestinal mucosa, adrenal cortex, the testes, and the ovaries. Cholesterol is composed of a fused ring system -cyclopentanoperhydrophenanthrene (CPPPMetabolism of Steroids11and Other LipidsCONTENTSSTEROID METABOLISMCholesterol Synthesis&IC AcdsPHOSPHOGLYCERIDE METABOLISMSynthesis of Simple Phosphog Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2 A (CoA).The major categories of steroids are based on the side chain attached to the C17 position of the CPPP nucleus:•Estrogens; (i.e., 18-carbon) steroids•Androgens; C19 steroids•Progesterone and adrenal cortical steroids; c2| steroids•Bile acids; C24 steroids•Cholesterol and cholecalciferol (not Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2 shown in Fig. 11-1);C27 steroidsThiolaseTwo molecules of acetyl-CoA condense to form acetoacetyl-CoA.fi-Hydroxy-fl-methylglutaryl (HMG)-CoA synthase.Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2
A third molecule of acetyl-CbA condenses with acctoacetyl-CoA to form p-hydroxy-B-methylglutaryl-CoA (HMG-CoA). Illis cytoplasmic form of HMG-CoA synMetabolism of Steroids11and Other LipidsCONTENTSSTEROID METABOLISMCholesterol Synthesis&IC AcdsPHOSPHOGLYCERIDE METABOLISMSynthesis of Simple Phosphog Ebook Elsevier''s integrated review biochemistry (2nd edition): Part 2c acid.PHARMACOLOGYStatin Side EffectsMetabolism of Steroids11and Other LipidsCONTENTSSTEROID METABOLISMCholesterol Synthesis&IC AcdsPHOSPHOGLYCERIDE METABOLISMSynthesis of Simple PhosphogGọi ngay
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