Ebook Fundamentals of biochemistry (5/E): Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Fundamentals of biochemistry (5/E): Part 2
Ebook Fundamentals of biochemistry (5/E): Part 2
CHAPTER 14Modern approves to understanding metabolism nclixfe the use of network theory to probe the functional impotence of interacting cellular comp Ebook Fundamentals of biochemistry (5/E): Part 2ponents, such as the yeast proteins shown here.HJWWCNG JECNG UNNĨRSITY 0= NOTRE PAVE / Sói™ SoureaIntroduction to MetabolismChapter Contents1Overview of MetabolismA Nutrition invoiwK Feed intake and useB Vitamins and Minerals Asss- Metabolic Reactionsc Metaooic Pathways Consist 0Í Series or Enzymati Ebook Fundamentals of biochemistry (5/E): Part 2c Reactions0 Thermodynamics Dictates the Drection and Regulatory Capacity or Metabolic Pathways£ Metaooic Flux Must Be Controlled2"High-Energy" CompouEbook Fundamentals of biochemistry (5/E): Part 2
ndsA ATP Has a H gh Phosphoryl Group-Transfer Potential8 Coupled Reactions Drtw Endergonic Processes c some Other Phosphorylated Compounds Haw High PhCHAPTER 14Modern approves to understanding metabolism nclixfe the use of network theory to probe the functional impotence of interacting cellular comp Ebook Fundamentals of biochemistry (5/E): Part 2uation Describes Oxdation-Reduction Reactionsc spontaneity Can Be Determined by Measurng Reduction Potential Differences4Experimental Approaches to the Studyof MetabolismA Labeled Metabolites Can Be TracedB Studying Metaboic Pathways Often Invokes Perturbing the Systemc Systems Biofegy Has Entered t Ebook Fundamentals of biochemistry (5/E): Part 2he study of MetaooismUnderstanding the chemical compositions and three-dimensional Structures of biological molecules is not sufficient to understandEbook Fundamentals of biochemistry (5/E): Part 2
how they are assembled into organisms or how they function to sustain life. We must therefore examine the reactions in which biological molecules are CHAPTER 14Modern approves to understanding metabolism nclixfe the use of network theory to probe the functional impotence of interacting cellular comp Ebook Fundamentals of biochemistry (5/E): Part 2nergy is generated from organic or other sources. Metabolism, the overall process through which living systems acquire and use free energy to carry out their various functions, is traditionally divided into two parts:1Catabolism, or degradation, in which nutrients and cell constituents are broken do Ebook Fundamentals of biochemistry (5/E): Part 2wn to salvage their components and/or to make energy available.2Anabolism, or biosynthesis, in which biomolecules are synthesized from simpler componeEbook Fundamentals of biochemistry (5/E): Part 2
nts.In general, catabolic reactions carry out the exergonic oxidation of nutrient molecules. The free energy thereby released is used to drive such enCHAPTER 14Modern approves to understanding metabolism nclixfe the use of network theory to probe the functional impotence of interacting cellular comp Ebook Fundamentals of biochemistry (5/E): Part 2xergonic and endergonic processes are often coupled through the intermediate synthesis of a "high-energy” compound such as ATP. This simple principle underlies many of the chemical reactions presented in the following chapters. In this chapter, we introduce the general features of metabolic reaction Ebook Fundamentals of biochemistry (5/E): Part 2s and the roles of ATP and other compounds as energy carriers. Because many metabolic reactions are also oxidation-reduction reactions, we review theEbook Fundamentals of biochemistry (5/E): Part 2
thermody namics of these processes. Finally, we examine some approaches to studying metabolic reactions.442Section 1 Overview of Metabolism1 Overview CHAPTER 14Modern approves to understanding metabolism nclixfe the use of network theory to probe the functional impotence of interacting cellular comp Ebook Fundamentals of biochemistry (5/E): Part 2 requirement for oxygen.•Mammalian nutrition involves the intake of macronutrients (proteins, carbohydrates, and lipids) and micronutrients (vitamins and minerals).•A metabolic pathway is a series of enzyme-catalyzed reactions, often located in a specific part of a cell.•The flux of material through Ebook Fundamentals of biochemistry (5/E): Part 2 a metabolic pathway vanes with the activities of the enzymes that catalyze irreversible reactions.•These flux-controlling enzymes are regulated by alEbook Fundamentals of biochemistry (5/E): Part 2
bstenc mechanisms, covalent modification, substrate cycling, and changes in gene expression.CHAPTER 14Modern approves to understanding metabolism nclixfe the use of network theory to probe the functional impotence of interacting cellular compCHAPTER 14Modern approves to understanding metabolism nclixfe the use of network theory to probe the functional impotence of interacting cellular compGọi ngay
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