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Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

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Nội dung chi tiết: Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

12Thyroid diseaseGarry McDowellAfter studying this chapter you should be able to:■Describe the structure and function of the thyroid gland■Explain the

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2e function of thyroid hormones■Outline the action of thyroid hormones and control of their secretion from the thyroid gland■Describe the conditions wh

ich lead to abnormal thyroid hormone produơion■Discuss the investigation of suspected thyroid dysfunctionIntroductionThe thyroid gland secretes thyroi Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

d hormones that are required for normal metabolism of body cells. Disorders of thyroid function can result in either inadequate or excess production o

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

f thyroid hormones causing altered cellular metabolism and development of associated clinical features.This chapter will describe the nature and role

12Thyroid diseaseGarry McDowellAfter studying this chapter you should be able to:■Describe the structure and function of the thyroid gland■Explain the

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2osis and monitoring of treatment will be discussed.12.1Structure of the thyroid glandThe thyroid gland IS found below the larynx and is a butterfly sh

aped gland composed of a right and left lobe on either side of the trachea Both lobes are joined by an isthmus in front of the trachea The normal thyr Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

oid gland weighs approximately 30 g and is highly vascularized, receiving 80-120 mL of blood per minute, as shown in Figure 12.1.12.1 STRUCTURE OF THE

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

THYROID GLANDThyroid cartilage of larynxRight lateral lobe of thyroid glandTracheaCommon carotid artery.-Internal jugular veinLeft lateral lobe of th

12Thyroid diseaseGarry McDowellAfter studying this chapter you should be able to:■Describe the structure and function of the thyroid gland■Explain the

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2ical sacs called thyroid follicles that make up most of the thyroid gland The wall of each follicle is composed mainly of follicular cells, most of wh

ich extend to the lumen of the follicle. Figure 12.2 shows the structure of thyroid follicles.Follicular cellFollicle containing thyroglobulinFIGURE 1 Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

2.2Histological structure of the thyroid gland showing the follicles in which thyroid hormones are made. Courtesy of Dr A L Bell. University of New En

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

gland College of Osteopathic Medicine, USA.32212 THYROID DISEASEA basement membrane surrounds each follicle. Follicular cells produce two hormones: th

12Thyroid diseaseGarry McDowellAfter studying this chapter you should be able to:■Describe the structure and function of the thyroid gland■Explain the

Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2hormones. The parafollicular cells or C-cells lie in between the follicles and produce a hormone called calcitonin, which regulates calcium homeostasi

s.SELF-CHECK 12.1What are the two cell types in the thyroid gland and what hormones do they secrete?12.2Thyroid hormones Ebook Fundamentals of biomedical science - Clinical Biochemistry: Part 2

12Thyroid diseaseGarry McDowellAfter studying this chapter you should be able to:■Describe the structure and function of the thyroid gland■Explain the

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