Ebook Pediatric drug doses (2nd edition): Part 2

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Ebook Pediatric drug doses (2nd edition): Part 2

17AntimyasthenicsCHAPTER1.EdrophoniumUse: Diagnosis of myasthenia gravis.Dosage: IV:•Infants: Initial dose of 0.1 mg, if no response then followed by

Ebook Pediatric drug doses (2nd edition): Part 2 0.4 mg, total dose is 0.5 mg.•Children: 0.04 mg/kg given over 1 minute, if no response within 45 seconds then followed by 0.16 mg/kg (Max: 10 mg tota

l).Brands: 10 mg ampoule; Tensilon.•May cause arrhythmias, hypotension, seizures, drowsiness, laryngospasm, bronchospasm, diaphoresis. Keep atropine r Ebook Pediatric drug doses (2nd edition): Part 2

eady for treatment of cholinergic crises resulting from overdoses.2.NeostigmineUse: Treatment ol myasthenia gravis, reversal ol nondepolarizing neurom

Ebook Pediatric drug doses (2nd edition): Part 2

uscular blocking agents.Dosage:•Myasthenia gravis: Diagnosis: IM, 0.025-0.04 mg/kg as a single dose. Treatment: IM, SC; 0.01-0.04 mg/kg q 2-4 hr and o

17AntimyasthenicsCHAPTER1.EdrophoniumUse: Diagnosis of myasthenia gravis.Dosage: IV:•Infants: Initial dose of 0.1 mg, if no response then followed by

Ebook Pediatric drug doses (2nd edition): Part 2dose: 5 mg). Use in conjunction with atropine or glycopyrrolate.Brands: 15 mg Tab; Prostigmin, Tilstigmin. 0.5 mg Inj; Myosligmin, Prostigmin.•Docs no

t antagonize succinylcholinc. Use with caution in patients of epilepsy, bradycardia, hypothyroidism, asthma.3.PyridostigmineUse: Treatment of myasthen Ebook Pediatric drug doses (2nd edition): Part 2

ia gravis, reversal ol neuromuscular blocking agents.Dosage:•Myasthenia gravis: In children 7 mg/kg/day in 5-6 divided doses.•Reversal of nondepolariz

Ebook Pediatric drug doses (2nd edition): Part 2

ing neuromuscular blockade: 0.1-0.25 mg/kg/dosc preceded by atropine or glycopyrrol ale.Brands: 30 and 60 mg Tab, Myestin.•May cause seizures, headach

17AntimyasthenicsCHAPTER1.EdrophoniumUse: Diagnosis of myasthenia gravis.Dosage: IV:•Infants: Initial dose of 0.1 mg, if no response then followed by

Ebook Pediatric drug doses (2nd edition): Part 2arial.3.MetronidazoleUse: Amoebiasis, giardiasis, trichomoniasis, SSTI, CNS infection, intra-abdominal in I ection, systemic anaerobic infections.Dosa

ge: Ebook Pediatric drug doses (2nd edition): Part 2

17AntimyasthenicsCHAPTER1.EdrophoniumUse: Diagnosis of myasthenia gravis.Dosage: IV:•Infants: Initial dose of 0.1 mg, if no response then followed by