Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

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Nội dung chi tiết: Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

Doctoral DissertationTumor antigen development for dendritic cell-based cancer immunotherapy against multiple myelomaDepartment of Molecular MedicineG

Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma Graduate School, Chonnam National UniversityHOANG My Dung42217Tumor antigen development for dendritic cell-based cancer immunotherapy against multiple

myelomaDepartment of Molecular MedicineGraduate School, Chonnam National UniversityHOANG My DungSupervised by Professor LEE Jo-JungA dissertation sub Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

mittedDoctor of Philosophy individuals below.in partial fulfillment of the requirements for the in Science, has been deemed acceptable by theCommittee

Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

in Charge :RHEE Joon IlaengNAM Jong-HeeCHUNG Ik-JooPARK Tn-KyiiLEE J?-Jung42217CONTENTSLIST OF FIGURES...............................................

Doctoral DissertationTumor antigen development for dendritic cell-based cancer immunotherapy against multiple myelomaDepartment of Molecular MedicineG

Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma 1PART I: Branched polyethylenimine-superparamagnetic iron oxide nanoparticles (bPEI-SPIONs) improve the immunogenicity of tumor antigens and enhance T

h 1 polarization of dendritic cells.............3LA.Introduction.................................................-1LB.Materials and Methods........... Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

..............................oLB. 1) Synthesis and characterization of bPEI-SPION.............5LB.2) Intracellular ferric iron measurement...........

Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

..........5LB.3) Confocal microscopy.......................................6LB.4) Assays of ROS generation..................................6LB.5) Gen

Doctoral DissertationTumor antigen development for dendritic cell-based cancer immunotherapy against multiple myelomaDepartment of Molecular MedicineG

Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma ein (Hsp) expression on rumor antigens........................................................7LB.8) Western blotting.................................

.........7 Tumor antigen development for dendritic cell based cancer immunotherapy against multiple myeloma

Doctoral DissertationTumor antigen development for dendritic cell-based cancer immunotherapy against multiple myelomaDepartment of Molecular MedicineG