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Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

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Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) yright © 2010. 2000. 1985 Elsevier Ltd. All rights reservedNo part of this publication may he reproduced. stored in a retrieval system or transmitted

in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher Permiss Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

ions may be sought directly from Elsevier’s Science fax (+44) (0) 1865 853333: email: pcrmission^elscvicr.com. Alternatively yon can submit your reque

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

st online by visiting the Elsevier web site at http://clscvier.com/locatc/iK-rmissions. and selecting Obtaining permission to use Elsevier materialNot

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in

rhe medical sciences, in particular, independent verification of diagnoses and drug dosages should be madeBritish Library Cataloguing in Publication Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

DataA catalogue record for this book is available from the British LibraryLibrary of Congress Cataloging-in-Publicarion DaraA catalog record for this

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

book is available from the Library of CongressFor information on all Elsevier publications visit our website at books.clscvicr.comPrinted and bound in

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) ookaid.org I wwwaabre.orgELSEVIER 522!ftil2 Sabre Foundation1.1ForewordThe text HtteroiydK chemistry by A. R. Katritzky and J. M. I.agowskt was the su

bject's first modern treatment; it appeared 50 years ago. treating structure, reactivity, and synthesis systematically in terms of molecular structure Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

. 1'his text and its sequels, which were translated into (Chinese. French. German. Greek. Italian. Japanese. Polish. Russian, and Spanish, revolutioni

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

zed the practice and leaching of the subject worldwide. The 1st Edition of Handbook of He/ervcycỉìc C/ưmiMy (I landbook-I) followed in 1985 as part of

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) e publication of CH EC-Ill in 2008.The importance and extent of the subject matter of heterocyclic chemistry continues to grow such that it is now cle

arly the largest subdivision of organic chemistry. It plays a crucial role in biochemistry - increasingly so in medicine -and manifest other areas of Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

chemistry as applied to subjects as diverse as construction and agriculture. Such is the rate of growth that this update is clearly needed.Handbook-Il

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

l retains the essentials of the treatments of Handbooks-! and -II in dividing the subject into the three main areas of structure, reactivity, and synt

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) ed and consulted.Handbook-111 has four authors; three have prime responsibility for one section each: A. R. for Structure, J. A. J. for Reactivity, an

d V. V. z. for Synthesis. Although much of rhe original content has been retained, each author has brought his own major experience throughout the rev Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

ision, rewriting, and insertion of new material into rhe old.Alan R. Katritzky. (Christopher A. Ramsden. John A. Joule, and Viktor V. Zhdankin2www.pdf

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

grip.comhttps: //k hoth u Vi en.com1.3Notes on the Arrangement of the Material in the HandbookArrangement of Material in the structure ChaptersThe Str

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) some sections have been largely rewritten whereas others have new material added with mostly minimum changes. New material has been selected to illus

trate principles and trends, or to introduce new developments in the subject. .Some material from 1 landbook-11 has been deleted and replaced by examp Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

les of more recent work. C11EC-1I1 has been the major source of new material and. in addition to references to the primary literature, relevant sectio

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

ns of CI1EC-111 arc widely cited throughout the chapters.In Chapter 2.1a new section on computer-aided techniques has been introduced. 'This gives an

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) a glossary of general terms used throughout rhe structure chapters and an indication of sections where examples can be found.Chapters 22-2.5 cover th

e structures and related properties of heterocycles according to ring size. Each chapter follow s the same general format beginning with a survey of p Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

ossible structures, their nomenclature, including common names, and an emphasis on rings of special importance. Next, sections on theoretical methods

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

arc subdivided into coverage of general trends, illustrated using the results of lluckcl and AMI calculations, followed by descriptions of rhe results

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) scopy) arc then followed by sections on spectroscopic methods (including 'H,NMR, IR, and I A) and mass spectrometry. Sections on thermodynamic aspects

includediscussions of aromariciry and anriaromariciry, and conformations of nonconjngarcd rings. Each chapter concludes w ith a discussion of tautome Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

rism, which is subdivided into prototropic and valence tautomerism. As appropriate for each ring category, prototropic tautomerism is further subdivid

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

ed into annular tautomerism, substituent tautomerism, and ring-chain tautomerism.Chapter 2.2 covers six-membered heterocycles. Chapters 2.3 and 2.4 co

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) ocycles has been increased. Recent developments in the measurement of aromaticity using energetic, structural, and magnetic indices arc discussed in C

hapter 22-2.4 and indices tabulated and compared. Chapter 2.5 covers small and large rings and includes heterocycles that arc formally antiaromatic if Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

planar. Throughout the structure chapters, numerical data useful to practicing heterocyclic chemists (c.g. bond lengths, chemical shifts, uv spectra)

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

have been presented in Tables for easy reference.Arrangement of Material in the Reactivity ChaptersThe Reactivity chapters in 1 landbook-111 follow t

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) subdivisions of the Reactivity sections have been retained. These include, where relevant, comparisons of heterocyclic reactivity w ith the chemistry

of benzenoid aromatic compounds and with carhonyl/cnol/cnaminc chemistry. The use of’nucleophilic attack on ring-or side-chain hydrogen.' has been ch Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

anged to ’base attack on ring- or side-chain hydrogen,’ the term ’nucleophile' being reserved for reactions at carbon (or nitrogen or sulfur).Reaction

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

s of organometallic nucleophiles arc reviewed mainly under ’Reactivity of Substituents: Metals and Metalloids’ - this is a change from the ilandbook-1

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010) ered partly under ’Reactivity of Substituents: I lalidcs' and partly in the metalloids sections. 'Transition metal-catalyzed reactions of stannanes, b

oronic acids, etc., arc considered under ’Reactivity of Substituents: Metals and Metalloids.’ 'These areas represent the largest proportion of the add Alan r katritzky, christopher a ramsden, john a joule, viktor v zhdankin handbook of heterocyclic chemistry, third edition (2010)

itional new material since I landbook-11 and arc certainly the most important.

ElsevierThe Boulevard. Langford Lane. Kidlington Oxford 0X5 1GB, I K Kadarweg 29, I’O Box 21L 1000 AE Amsterdam. The NetherlandsThird edition 2010Copy

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