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N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

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N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) HIBAEVORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BEdited by N. K. Kochetkov and E. I. BudovskiiTranslated from Russian by Basil HaighTranslation edited b

y Lord Todd and D. M. BrownT PLENUM PRESS . London and New York .1972Plenum Publishing Company Ltd. Davis House 8 Scrubs Lane Harlesden London NW10 6S N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

E Tel. 01-969-4727U.S. Edition published by Plenum Publishing Corporation 227 West 17th Street New York, N.Y. 10011ISBN-13: 978-1-4684-2975-6 e-ISBN-1

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

3: 978-1-4684-2973-2DOI: 10.1007/978-1-4684-2973-2© 1972 by Plenum Publishing Company Ltd.Softcover reprint of the hardcover 1st edition 1972All right

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) ical, photocopying, microfilming, recording or otherwise, without written permission from the publisher.Library of Congress Catalog Card Number 77-178

777The original Russian text was first published by Khimiya Press in Moscow in 1970. The present translation is published under an agreement with Mezh N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

dunarodnaya Kniga, the Soviet book export agency.H. K. KoveTKOQ, 3, H' BydoecKuă,OPrAHHHECKAfl XHMHfl HYKJIEHHOBblX KHCJIOTORGANICHESKAYA KHĨMIYA NƯKL

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

EINOVYKH KISLOTSet in cold type by Plenum Publishing Company LtdForewordThe study of nucleic acids is one of the most rapidly developing fields in mod

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) mber of published works on the subject, including many outstanding monographs and surveys. The pathways of synthesis and metabolism of nucleic acids a

nd the many and varied biological functions of these biopolymers are examined with the utmost detail in the literature. Nearly as much attention has b N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

een paid to the macromolecular chemistry of the nucleic acids: elucidation of the size and shape of their molecules, the study of the physicochemical

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

properties of their solutions, and the appropriate methods to be used in such research.The surveys of the chemistry of nucleic acids which have been p

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) less attention has been paid to the synthesis of polynucleotides. There is yet another highly important aspect of the chemistry of nucleic acids which

is still in the formative stage, the study of the reactivity of nucleic acid macromolecules and their components. This can make an important contribu N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

tion to the determination of the structure of these remarkable biopolymers and to the correct understanding of their biological functions. Research in

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

this direction has begun to make rapid progress in recent years and its scope has increased enormously. Nevertheless, this aspect of nucleic acid che

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) d to more or less specialized problems.The authors of this present monograph have tried to remedy this deficiency, while recognizing the difficulty of

the task they have undertaken. The book deals with reactions of the nucleic acids and their components; these reactions lead to structural changes in N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

nucleic acids; to their chemical modificationAlthough the ultimate purpose of the book is to familiarize the reader with the chemical reactions of th

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

e polynucleotides, most of the material is nevertheless concerned with chemical conversions of theVVIF0RW0RDmonomeric components of nucleic acids; nuc

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) e reactions of their monomeric components. Moreover, the bulk of the research at the present time is still being undertaken at the monomer level, and

only a relatively few studies of the chemical modification of the biopolymers themselves have been made. Nevertheless, the facts which are known conce N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

rning reactions of polymers, especially in cases where the problem has been studied in considerable depth and detail, can shed light on the structure

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

of nucleic acids. What is more, they can point the way to a rational use of the corresponding reactions in the study of the biological function of nuc

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) eic acids. The conformation and electronic structure of the monomers, the reactivity of the heterocyclic bases (looking at the problem also from the s

tandpoint of quantum chemistry), and the important question of noncovalent interactions in the polymer chain of nucleic acids all receive attention. I N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

t was thought advisable to begin the first part of the book with a brief survey of the classification and distribution of nucleic acids and the princi

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

ples governing the establishment of their primary structure.Part B (Chapters 5-12) is concerned with the special organic chemistry of the nucleic acid

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972) apter is devoted to a brief account of the photochemistry of nucleic acids.A list of recommended symbols and abbreviations for the polynucleotides and

their components and derivatives is included. N k kochetkov, e i budovskii (auth ), n k kochetkov, e i budovskii (eds ) organic chemistry of nucleic acids part b springer US (1972)

ORGANIC CHEMISTRY OF NUCLEIC ACIDS Part BContributors:N. K. KOCHETKOV, E. I. BUDOVSKII, E. D. SVERDLOV, N. A. SIMUKOVA,M. F. TURCHINSKII, AND V. N. SH

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