Study on the intestinal absorption of small and oligopeptides in rats

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Study on the intestinal absorption of small and oligopeptides in rats

Study on the intestinal absorption of smalland oligopeptides in ratsVu Thi HanhKyushu University2017List of contentsChapter I Introduction............

Study on the intestinal absorption of small and oligopeptides in rats ..................................................1Chapter IIApplication of a standard addition method for quantitative mass spectrometric assay of di

peptides.....................................171Introduction.......................................................172Materials and Methods........... Study on the intestinal absorption of small and oligopeptides in rats

..................................212.1.Materials and instrumentation....................................212.2.Preparation of peptide standard and soy

Study on the intestinal absorption of small and oligopeptides in rats

bean hydrolysate solutions.222.3.Derivatization of dipeptides with TNBS...........................222.4.LC-TOF-MS analysis............................

Study on the intestinal absorption of smalland oligopeptides in ratsVu Thi HanhKyushu University2017List of contentsChapter I Introduction............

Study on the intestinal absorption of small and oligopeptides in rats es.......243.2.Application of a standard addition method for quantitative MS assay ofdipeptides in soybean hydrolysate................................

.....304Summary...........................................................36Chapter 111Intestinal absorption of oligopeptides in spontaneously hyperte Study on the intestinal absorption of small and oligopeptides in rats

nsive rats .371Introduction.........................................................372Materials and Methods..........................................

Study on the intestinal absorption of small and oligopeptides in rats

......392.1.Materials..........................................................402.2.Animal experiments...............................................

Study on the intestinal absorption of smalland oligopeptides in ratsVu Thi HanhKyushu University2017List of contentsChapter I Introduction............

Study on the intestinal absorption of small and oligopeptides in rats 3Results and Discussion...............................................433.1.Absorption of a tripeptide model Gly-Sar-Sar in spontaneously hypertensive

rats.....................................................................433.2.Absorption of oligopeptide models Gly-Sar-Sar-Sar and Gly-Sar-Sar-Sar-S Study on the intestinal absorption of small and oligopeptides in rats

ar in spontaneously hypertensive rats...................................484Summary..............................................................54Chap

Study on the intestinal absorption of small and oligopeptides in rats

ter IVEffect of aging on intestinal absorption of peptides in spontaneously hypertensive rats........................................................5

Study on the intestinal absorption of smalland oligopeptides in ratsVu Thi HanhKyushu University2017List of contentsChapter I Introduction............