Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLR
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Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLR
THE CHEMISTRY OF BRIAREUM ASBESTINUM byMelody D. RondeauA Thesis Submitted to the Faculty of theCharles E. Schmidt College of ScienceIn Partial Fulfil Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRllment of the Requirements for the Degree ofMaster of ScienceFlorida Atlantic UniversityBoca Raton. FL41122THE CHEMISTRY OF BRIAREUM ASBESTINUM byMelody D. RondeauThis thesis was prepared under the direction of the candidate’s thesis advisor, Dr. Lyndon M. West, Department of Chemistry and Biochemis Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRtry, and has been approved by the members of her supervisory committee. It was submitted to the Charles E. Schmidt College of Science and was acceptedDeyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLR
in partial fulfillment of the requirements for the degree of Master of Science.SUPERVISORY COMMITTEE:Gar/W. Pdrfy, Ph.D.Dean, Charles E. Schmidt CollTHE CHEMISTRY OF BRIAREUM ASBESTINUM byMelody D. RondeauA Thesis Submitted to the Faculty of theCharles E. Schmidt College of ScienceIn Partial Fulfil Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRsuccess as a graduate student. First, I would like to thank my advisor, Dr. Lyndon M. West for his support, guidance and, most of all, patience. I would also like to thank my graduate committee. Dr. Charles Carraher and Dr. Frank Mari: your consideration and input were invaluable.I would like to tha Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRnk Dr. Salvatore Lepore for always being available to lend a listening ear. Your advice always motivated and encouraged me.I am indebted to the memberDeyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLR
s of the West laboratory; Rian Meginley, Tifanie Vansach, Andrew Hall, Rolando Rueda de Leon, Long Zhang, and Yangqing He as well as Dr. Prasoon GuptaTHE CHEMISTRY OF BRIAREUM ASBESTINUM byMelody D. RondeauA Thesis Submitted to the Faculty of theCharles E. Schmidt College of ScienceIn Partial Fulfil Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRxtend a special thank you to my family and friends. I really could not have done it without you. I am so fortunate to be surrounded by such support.Finally, I would like to thank Michael Rondeau for his love and encouragement throughout this journey.HiABSTRACTAuthor:Melody D. RondeauTitle:The Chemis Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRtry of Bnareum asbestinumInstitution:Florida Atlantic UniversityThesis Advisor:Dr. Lyndon M. WestDegree:Master of ScienceYear:2012Briareum asbestinum,Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLR
a soft coral, is a rich source of diterpenoid natural products. The secondary metabolites of B. asbestinum fall into four classes; asbestinins, briarTHE CHEMISTRY OF BRIAREUM ASBESTINUM byMelody D. RondeauA Thesis Submitted to the Faculty of theCharles E. Schmidt College of ScienceIn Partial Fulfil Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRbago. Our group recently isolated briareolate esters from a specimen collected off the coast of Boca Raton, Florida.To determine whether location has an impact on the chemistry produced by the organism, a method to discern between chemotypes was sought. Several techniques including thin layer chroma Deyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLRtography (TLC), high performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), and sclerite analysis were employed, with NMR being tDeyle-et-al.-2007.-Florida-Adaptive-Planning-for-SLR
he most successful method.ivTHE CHEMISTRY OF BRIAREUM ASBESTINUM byMelody D. RondeauA Thesis Submitted to the Faculty of theCharles E. Schmidt College of ScienceIn Partial FulfilTHE CHEMISTRY OF BRIAREUM ASBESTINUM byMelody D. RondeauA Thesis Submitted to the Faculty of theCharles E. Schmidt College of ScienceIn Partial FulfilGọi ngay
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