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Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

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Nội dung chi tiết: Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1SCOVERYSixth EditionVolume 1: Drug DiscoveryEdited byDonald J. AbrahamDepartment of Medicinal Chemistry School of PharmacyVir * ar mmnnwPiiJth J Ipive

rsifyBurger's Medicinal Chemistry and Drug Discovery is available Online in full color at www.mrw.interscience.wiley.com/bmcdd.WILEY"INTERSCIENCEA Joh Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

n Wiley and Sons, Inc., PublicationBURGH* MEMORIAL EDITIONThe Sixth Edition of Burger's Medicinal Chemistry and Drug Discovery is being designated as

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

a Memorial Edition. Professor Alfred Binger was born in Vienna. Austria on September 6, 1905 and died on December 30, 2000. Dr. Burger received his Ph

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1929. During his early years al UVA, he synthesized fragments of the morphine molecule in an attempt to find the analgesic pharmacophore. He joined the

ƯVA chemistry facultyin 1938 and served the department until his retirement in 1970. The chemistry department al UVA became the major academic traini Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

ng ground for medicinal chemists because of Professor Burger.Dr. Burger's research focused on analgesics. antidepressants, and chemotherapeutic agents

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

. He is one of the few academicians to have a drug, designed and synthesized in hislaboratories, brought to market [Parnate, which is the brand name f

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1world. He founded the Journal of Medicinal Chemistry, Medicinal Chemistry Research, and published the first major reference work "Medicinal Chemistry"

in two volumes in 1951. His last published work, a book, was written al age 90 (Understanding Medications: What the Label Doesn't Tell You. June 1995 Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

). Dr. Burger received the Louis Pasteur Medal of the Pasteur Institute and the Amer', ican Chemical Society Smissman Award. Dr. Burger played the vio

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

lin and loved classical music. He was married for 65 years to Frances Page Burger, a genteel Virginia lady who always had a smile and an open house fo

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1hree and a half years to update the fifth edition of Burger's Medicinal Chemistr)- and Ding Discovery; rhe sixth edition has several new and unique fe

atures. For the first time, there will be an online version of this major reference work. The online version will permit updating and easy access. For Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

the first lime, all volumes are structured entirely according to content and published simultaneously. Our intention was to provide a spectrum of fie

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

lds that would provide new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists entry to their subjects of interest

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1ensive and useful published to date. To accomplish this goal, we expanded the content from 69 chapters (5 volumes) by approximately 50% (to over 100 c

hapters in 6 volumes). We are greatly in debt to the authors and editorial board members participating in this revision of the major reference work in Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

our field. Several new subject areas have emerged since the fifth edition appeared. Proteomics, genomics, bioinformatics, combinatorial chemistry', h

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

igh-throughput screening, blood substitutes, allosteric effectors as potential drugs, cox inhibitors, the statins, and high-throughput pharmacology ar

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1ion, we devote an entire subsection of Volume 4 to cancer research; we have also reviewed the major published Medicinal Chemistry and Pharmacology tex

ts to ensure that we did not omit any major therapeutic classes of drugs. An editorial board was constituted for the first time to also review and sug Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

gest topics for inclusion. Their help was greatly appreciated, rhe newest innovation in this series will be the publication of an academic, '’textbook

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

-like*' version tilled, "Burger's Fundamentals of Medicinal Chemistry." The academic text is to be published about a year after this reference work ap

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1friends, and associates to thank for their assistance. First and foremost is Assistant Editor Dr. John Andrako, Professor emeritus, Virginia Commonwea

lth University, School of Pharmacy. John and I met almost every' Tuesday for over three years to map out and execute the game plan for the sixth editi Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

on. His contribution to the sixth edition cannot be understated. Ms. Susanne Steitz, Editorial Program Coordinator at Wiley, tirelessly and meticulous

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1

ly kept us on schedule. Her contribution was also key in helping encourage authors to return manuscripts and revisions so we could publish the entire

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

Ebook Burger’s medicinal chemistry and drug discovery (6/E): Part 1 Roy Vaz. John Mason. Yvonne Martin. John Block, and HugoixXPreface

Burger’SSixth EditionMedicinal QjChemistry E®rugDiscoveryEdited byDonald J. AbrahamVOLUME 1Drug DiscoveryI ® IIBURGER'SMEDICINAL CHEMISTRYAND DRUG DIS

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