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Ebook Clinical and diagnostic virology: Part 2

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Nội dung chi tiết: Ebook Clinical and diagnostic virology: Part 2

Ebook Clinical and diagnostic virology: Part 2

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

Ebook Clinical and diagnostic virology: Part 2tary bodies (LB), which are electron-dense infectious structures and reticulate bodies (Rli), which arc non-infectious, intracellular forms. Elementar

y bodies attach to the cell to initiate cell infection. Once inside the cells they differentiate into RBs; RBs divide by binary fission and subsequent Ebook Clinical and diagnostic virology: Part 2

ly differentiate back to EBs to be released from the cell to initiate further infection.clilamydia belong to the family Chlamydiaceae, wliich has two

Ebook Clinical and diagnostic virology: Part 2

genera:1Chlamydia - which has one species c. trachomatis, c. trachomatis is further subdivided into scrovars.Serovars A, B, Ba and c cause trachoma (a

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

Ebook Clinical and diagnostic virology: Part 2pathy in the tropics.2Chlamydophita - species in the genus arc:Ch. psittaci - natural infection in birds, both psittacinc (parrots, budgerigars etc.)

and other birds (e.g. pigeons). Human infection is acquired as a zoonosis from birds.Ch. pneumoniae - is a human pathogen.Ch. abortus - primarily infe Ebook Clinical and diagnostic virology: Part 2

cts sheep and causes abortion in pregnant ewes (hence rhe name), human infection is accidental from sheep.Ch. caviae - causes infection in guinea pigs

Ebook Clinical and diagnostic virology: Part 2

, but does not cause human infection.EpidemiologyBoth chlamydia and chlamydophila are prevalent worldwide. Trachoma is a disease of underdeveloped and

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

Ebook Clinical and diagnostic virology: Part 2y transmitted infection (STI) in the UK. with between 10 and 15% of all 15 to 25 year-olds being infected at any given rime. Lymphogranuloma venereum

is limited purely to those who have partners from tropical countries as their sexual contacts.Chlamydophila psittaci and Ch. pneumoniae are prevalent Ebook Clinical and diagnostic virology: Part 2

worldwide; about 60-80% of people worldwide acquire Ch. pneumoniae infection, the incidence being 1-2% per year.122 Section 2: Other related agentsTab

Ebook Clinical and diagnostic virology: Part 2

ic 29.1. Infections due to Chlamydia and Chlamydophila species.AgentClinical infectionRoute of spreadc. trachomatis A, B, Ba, cTrachomaInfected fomite

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

Ebook Clinical and diagnostic virology: Part 2larged inguinal lymph nodesSexualCh. psittaciFebrile illness, atypical pneumonia, rarely endocarditisRespiratory('ll. pneumoniaeUpper respiratory trac

t infection or atypical pneumoniaRespiratoryCh. abortusFebrile illness, miscarriage in pregnancyRespiratoryClinicalSec Table 29.1.Chlamydia trachomati Ebook Clinical and diagnostic virology: Part 2

sTrachomaTills is an infection of childhood in the tropics. Trachoma is spread as a result of poor hygiene tlưough infected fomiles or close personal

Ebook Clinical and diagnostic virology: Part 2

contact. Flies are an important route of spread for trachoma, as they can carry rhe bacteria from person to person. Active trachoma presents as follic

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

Ebook Clinical and diagnostic virology: Part 2acture. This in turn results in the eyelashes constantly nibbing against the cornea (trichiasis) and leads to blindness in adult life.Genital chlamydi

a infectionThose who have unprotected casual sexual intercourse with multiple partners are the most at risk.Male genital infection is mostly asymptoma Ebook Clinical and diagnostic virology: Part 2

tic. Clinical infection presents as urethritis. Chlamydia infection is the commonest cause of non-specific urethritis (NSU) in males. Infection may sp

Ebook Clinical and diagnostic virology: Part 2

read to the upper genital tract and cause epididymo-orchitis and prostatitis and may cause male infertility. Inclusion conjunctivitis (Fig. 29.1) and

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

Ebook Clinical and diagnostic virology: Part 2cervicitis with cervical discharge is the most common presentation, urethritis being relatively uncommon in females. If untreated, ascending infection

can lead to salpingitis (infection of the Fallopian tubes) and pelvic inflammatory disease (PIT)).Chapter 29: Chlamydia 123Fig. 29.1. Chlamydia trach Ebook Clinical and diagnostic virology: Part 2

omatis conjunctivitis. (See Fig. 3 in colour plate section)

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

Section 2 - Other related agents29 ChlamydiaChlamydia arc obligate intracellular Gram-negative bacteria. They have a dimorphic growth cycle of element

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