Ebook Rapid clinical pharmacology - A student formulary: Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Rapid clinical pharmacology - A student formulary: Part 2
Ebook Rapid clinical pharmacology - A student formulary: Part 2
INFECTIONS 65AciclovirMECHANISM OF ACTION Synthetic analogue of guanosine, which is phosphorylated to become an active compound, aciclovir triphosphat Ebook Rapid clinical pharmacology - A student formulary: Part 2te. Aciclovir triphosphate competes with the natural nucleotide as a substrate to viral DNA polymerase and thus inhibits viral DNA replication.INDICATIONS•Treatment and prophylaxis of herpes simplex infections•Treatment of herpes zoster and varicella infectionsCAUTIONS AND CONTRA-INDICATIONS•Hyperse Ebook Rapid clinical pharmacology - A student formulary: Part 2nsitivity to aciclovir•Caution in renal impairment (dose adjustment may be required)SIDE-EFFECTS•Gl disturbance•Headache and dizziness•Rash•Fatigue•FeEbook Rapid clinical pharmacology - A student formulary: Part 2
ver•Renal failureMETABOLISM AND HALF-LIFE ly, is between 2.5-311. Most of the drug is excreted unchanged in urine.MONITORING Regular monitoring of renINFECTIONS 65AciclovirMECHANISM OF ACTION Synthetic analogue of guanosine, which is phosphorylated to become an active compound, aciclovir triphosphat Ebook Rapid clinical pharmacology - A student formulary: Part 2osporin or tacrolimusIMPORTANT POINTS•Maintain adequate hydration in patients on high doses or with renal failure (to reduce the risk of nephrotoxicity)•Elderly patients are at risk of neurological rear lions due Io reduced renal font lion and hence clearance. Examples of neurological symptoms inclu Ebook Rapid clinical pharmacology - A student formulary: Part 2de agitation, confusion, tremor, ataxia, convulsions and encephalopathy•IV treatment for 10 days is usually required for encephalitis•Can be given topEbook Rapid clinical pharmacology - A student formulary: Part 2
ically for skin and eye disease66 INFECTIONSAminoglycosidesEXAMPLES Gentamicin, tobramycin, amikacin, neomycin, streptomycinM ECH ANISM OF ACTION BactINFECTIONS 65AciclovirMECHANISM OF ACTION Synthetic analogue of guanosine, which is phosphorylated to become an active compound, aciclovir triphosphat Ebook Rapid clinical pharmacology - A student formulary: Part 2 mRNA translation IS disrupted.INDICATIONS•Septicaemia•Biliary tract infection•Acute pyelonephritis and prostatitis•Endocarditis•Adjunct in Listeria meningitisCAUTIONS AND CONTRA-INDICATIONS•Myasthenia gravis (aminoglycosides can impair neurotransmission within muscles) Ebook Rapid clinical pharmacology - A student formulary: Part 2INFECTIONS 65AciclovirMECHANISM OF ACTION Synthetic analogue of guanosine, which is phosphorylated to become an active compound, aciclovir triphosphatGọi ngay
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