Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
Cancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. Lo Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2ouis.•Missouri. U.S.A.I.INTRODUCTIONThe most common type of cancer affecting the oral cavity and oropharynx is squamous cell carcinoma (SCO. which is estimated to constitute approximately 94% of all oral malignancies (1). Because of this dominance, the term "oral cancer" is used synonymously with or Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2al see (2). Others, less commonly encountered carcinomas, are malignant melanoma and neuroendocrine carcinoma, which will be discussed later in this cEbook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
hapter. Carcinomas of minor salivary glands are detailed in the respective chapter in the text.see occurring at different anatomic subsites in the oraCancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. Lo Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2address these various tumors collectively. The following discussion will address in details each individual carcinoma by its respective site of incidence. The following is á list of these entities:sec of the oral cavity:1see of the lip2sec of the buccal mucosa3see of the floor of the mouth (FOM) and Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2 oral tongue (OT)4sec of the gingival and alveolar mucosa5sec of the hard palate6sec of the retromolar trigonsec of the oropharynx:1sec of soft palateEbook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
and uvula2see of the oropharyngeal wall3sec of tonsils and base of tongueKeratinizing squamous cell carcinoma (KSCC) is the prototype and the most coCancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. Lo Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2thologic, demographic and epidemiologic features of these variants will be addressed here. The following is a list of these variants:1Nonkeratinizing squamous cell carcinoma (NKCa)2Basaloid squamous carcinoma (BSC)3Adenosquamous carcinoma (ASC)4Adenoid squamous carcinoma5Verrucous carcinoma (VC)6Pap Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2illary’ squamous carcinoma7Spindle cell (sarcomatoid) carcinomaII.ANATOMY OF THE ORAL CAVITY AND OROPHARYNXAccording to the American Joint Committee oEbook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
n Cancer Staging, the oral cavity extends from the skin vermilion junction of the lips to the junction of the hard and soft palate above and to the liCancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. Lo Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2per alveolar ridge, retromolar gingival [retromolar trigone (RMT)]. FO.M. hard palate, and anterior two-thirds of the tongue (the OT) (Figs. 1. 2).The oropharynx extends from the plane of the hard palate superiorly to the plane of the hyoid bone inferiorly (Fig. 3). and is continuous with the oral c Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2avity through an opening called the faucial isthmus. The oropharynx is separated from the oral cavity by the junction of the soft and hard palates supEbook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
eriorly, the line of the circumvallate papillae inferiorly, and the anterior pillars of the fancies laterally.The oropharynx encompasses three main reCancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. Lo Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2 soft palate and uvula, the palatine tonsils, and their anterior and posterior pillars (Fig. 4). Although the R.MT is technically a component of the oral cavity, carcinomas in this location often involve adjacent oropharyngeal sites and behave more like oropharyngeal tumors (Fig. 4).III.EPIDEMIOLOGY Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2 AND ETIOLOGYOral cancer is an important global health concern accounting for an estimated 275.000 cases and 12S.OOO deaths annually (3-5). Cancer ofEbook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
the mouth and pharynx ranks sixth overall in the world. Its incidence varies markedly by geographic region.286El-Mofty and LewisFigure 1 Diagram showiCancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. Lo Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2lơ/rer lip. Abbreviations: OT. oral tongue; FOM. floor of the mouth.disease 10 years later than men (8). Changes in incidence-age have been observed during an approximately 30-year period. Using the 1973-2001 surveillance. epidemiology, and end results (SEER) database, a statistically significant in Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2crease in oropharyngeal carcinoma in young patients of 20 to 44 years was observed. No similar increase was evident in oral see (9). Another study fouEbook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2
nd a significant annual increase in tonsillar see in men. but not women, who are younger than 60 years. Again, no similar increase was observed in oraCancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. Lo Ebook Surgical pathology of the head and neck (Vol 1 - 3/E): Part 2l and ethnic differences in the prevalence of oral .' pharynx cancer may be related to social and cultural practices as well as socioeconomic factors.Cancer of the Oral Cavity and OropharynxSamir K. El-Mofty and James s. Lewis. Jr.Department of Pathology and Immunology. Washington University. St. LoGọi ngay
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