Open Source Synthetic Biology- Problems and Solutions
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Open Source Synthetic Biology- Problems and Solutions
Open Source Synthetic Biology- Problems and Solutions
Seton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutionsthan R. FitzpatrickSeton Hall LawFollow this and additional works at: https://scholarship.shu.edu/student scholarshipRecommended CitationHttpatnck, Ethan R„ 'Open Source Synthetic Biology: Problem* and Solution*' (2013). Low School SWenf Scholarship. 47.https: //ỉcholarship.shu.edu /student_scholare Open Source Synthetic Biology- Problems and Solutionshlp/47Open Source Synthetic Biology: Problems and Solutions Ethan R. Fitzpatrick*I. IntroductionIn May 2010, the J. Craig Venter Institute announced tOpen Source Synthetic Biology- Problems and Solutions
he creation of a simple bacterial cell entirely controlled by a chemically synthesized genome.* 1 The scientists started with the digital information Seton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutionss genome." The synthetic genome was then inserted into a host bacterium that had its native DNA removed? The resulting man-made bacterium was able to replicate itself using only the synthetic genome.4 Advances in the ability to synthesize genome-length strands of DNA have coincided with a growing un Open Source Synthetic Biology- Problems and Solutionsderstanding of the functions of individual genes and gene networks. With the available knowledge of how whole genomes function and the technical capabOpen Source Synthetic Biology- Problems and Solutions
ility of synthesizing whole genomes, it will be possible to digitally design novel organisms to perform some desired function and then manifest that sSeton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutionsigned genome sequences. DNA sequencing of a cellular genome allows storage of the♦J.D. Candidate. May 2013. Seton Hall University School of Law: Ph.D.. University of Medicine and Dentistry of New Jersey. 2010. B.s. Rider University. 2002. Thanks to Professor Jordan Paradise for her guidance. Becky G Open Source Synthetic Biology- Problems and Solutionsanbotto tor her comments and encouragement, and Desiree Grace for her thorough editing and assitance.1 D.G. Gibson et al.. Creation of a Bacterial CelOpen Source Synthetic Biology- Problems and Solutions
l Controlled by a Chemically Synthesized Genome. 329 SCIENCE 52 (20101.-Jrf.■ Matthias Heinemann & Sven Panke. Synthetic Biology—Putting Engineering ISeton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutions developed should be applicable to the synthesis and transplantation of more novel genomes as genome design processes."4’This ultimate goal of designing novel synthetic organisms using the technology of synthetic biology sounds like pure science fiction, but it is entirely possible and would have an Open Source Synthetic Biology- Problems and Solutions enormous impact on biotechnology and medicine. Synthetic organisms might be designed to create new sources of food, fuel, and medicine that current tOpen Source Synthetic Biology- Problems and Solutions
echnology is not capable of producing. Additionally, these benefits will arrive with incredible speed, efficiency, and cost effectiveness. Designing wSeton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutions the field of biotechnology, or more recently, the emerging technology of synthetic biology in its earliest phase. In order to make the possibilities of synthetic biology a reality in the least amount of time, one organization—the BioBricks Foundation—is attempting to protect this emerging field fro Open Source Synthetic Biology- Problems and Solutionsm the potential stifling effects of DNA-patents byr establishing an open source movement.7 * 9 The hope is that an open-source synthetic biology commoOpen Source Synthetic Biology- Problems and Solutions
ns would encourage innovation in ways similar to the wildly successful open source software movement.10 Towards that end. a similar open-source approaSeton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutionsent. These problems include incentivizing entities to participate, maintaining openness once it is established, and creating useable biomedical products.7 /J. at 52.* id.9 About theBioBricki Foundation. B1OB1UCKS.ORG. http: biobricks.org about-foundation (last visited Teb. 11.2Pan II of this Comment Open Source Synthetic Biology- Problems and Solutions provides an overview of the technology of synthetic biology and explains why it is important. Part III introduces the current movement towards open sOpen Source Synthetic Biology- Problems and Solutions
ource synthetic biology, as established by the BioBricks Foundation, and Part IV describes the past strategies used to establish and maintain other anSeton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutionssed approach to establish and maintain a commons. Part V then assesses whether these approaches to maintaining a synthetic biology commons are possible, and if so. what problems might be unique to synthetic biology. Part VI then proposes a wholly novel strategy to advance the progress of synthetic b Open Source Synthetic Biology- Problems and Solutionsiology. This strategy uses an open-source property-right hybrid approach, under the auspices of a standard setting organization, in order to overcomeOpen Source Synthetic Biology- Problems and Solutions
problems that cannot be addressed under the three previously described strategies. The Comment then concludes.II. Synthetic Biology: What is it and WhSeton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEt Open Source Synthetic Biology- Problems and Solutionsctions for life.1' The DNA language uses four nucleotides—adenine, thymine, cytosine, and guanine—organized in specific sequences to compose the genes responsible for heritable traits.1 The DNA sequence of an organism gets copied with an extremely high fidelity, averaging only one nucleotide error*• Open Source Synthetic Biology- Problems and Solutions BRUCE ALBERTS ET AL.. MOLECULAR Biology of the cell 193 (4th ed. 2002 >.13 Id at 194.3https://khothuvien.cori!Seton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEtSeton Hall UniversityeRepository (a) Seton HallLaw School Student ScholarshipSeton Hall Law2013Open Source Synthetic Biology: Problems and SolutionsEtGọi ngay
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