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Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

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Nội dung chi tiết: Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

Fatty Acid and10Triglyceride MetabolismCONTENTSFATTY ACID METABOLISMPathway Reaction Steps in Fatty Acid Synthesis Acetyl Coenzyme A to PalmitateRegul

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2lated Reactions in Fatty Acid Synthesis Acetyl-Coenzyme A CarboxylaseUnique Charactenstics of Fatty Acid SynthesesInterface with Other PathwaysFATTY A

CID MOBILIZATION AND OXIDATIONPathway Reaction Steps in Fatty Acid OxidationPalmitate to Acetyl Coenzyme A and Ketone BodiesRegulated Reactions in Fat Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

ty Acid Oxidation-Hormone-Sensrtive LipaseUnique Characteristics of Fatty Acid Oxidat onInterface with Other PathwaysRELATED DISEASES OF FATTY ACID ME

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

TABOLISMMedium Cham Acyl Coenzymc A Dehydrogenase DeficiencyJamaican Vomiting SicknessZellweger SyndromeCarnitine DeficiencyRefsum Disease•• FATTY ACI

Fatty Acid and10Triglyceride MetabolismCONTENTSFATTY ACID METABOLISMPathway Reaction Steps in Fatty Acid Synthesis Acetyl Coenzyme A to PalmitateRegul

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2n pathway intermediates and allows separate regulation of both pathways. However, since the precursor for fat synthesis, acctyl-cocnzymc A (CoA), aris

es in the matrix, it must first be transported to the cytoplasm for incorporation into a fatty acid. Likewise, free fatty acids (FFAs) mobilized for o Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

xidation must be transported into the mitochondrion to undergo oxidation. Each of the fatty acid metabolic pathways must therefore be preceded by a tr

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

ansport process. (Note: The synthetic and oxidative pathways are treated separately to facilitate comparisons.)HISTOLOGYRed Blood Cell MetabolismRed b

Fatty Acid and10Triglyceride MetabolismCONTENTSFATTY ACID METABOLISMPathway Reaction Steps in Fatty Acid Synthesis Acetyl Coenzyme A to PalmitateRegul

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2hway Reaction Steps in Fatty Acid Synthesis—Acetyl-Coenzyme A to PalmitateAcetyl-Coenzyme A ShuttleFour reactions shuttle acetyl-CoA from mitochondria

l matrix to cytoplasm (Fig. 10-1).Citrate synthaseAcetyl-CoA (e.g., from glucose following a meal) is condensed with oxaloacetate to form citrate. Cit Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

rate is then transported through the mitochondrial membrane to the cytoplasm.Citrate cleavage enzyme (citrate lyase)Acetyl-CoA and oxaloacetate are re

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

generated from citrate in the cytoplasm in a reaction that requires adenosine triphosphate (ATP) and CoA.Malate dehydrogenaseOxaloacetate is reduced w

Fatty Acid and10Triglyceride MetabolismCONTENTSFATTY ACID METABOLISMPathway Reaction Steps in Fatty Acid Synthesis Acetyl Coenzyme A to PalmitateRegul

Ebook Elsevier’s integrated review biochemistry (second edition): Part 2e decarboxylation with malic enzyme.Malic enzymeOxidative decarboxylation of malate produces pyruvate, co2, and nicotinamide adenine dinucleotide phos

phate (NADPH). The pyruvate is transported back into the mitochondrion and converted back to oxaloacetate with pyruvate carboxylase.82 Fatty Acid and Ebook Elsevier’s integrated review biochemistry (second edition): Part 2

Triglyceride Metabolism

Fatty Acid and10Triglyceride MetabolismCONTENTSFATTY ACID METABOLISMPathway Reaction Steps in Fatty Acid Synthesis Acetyl Coenzyme A to PalmitateRegul

Fatty Acid and10Triglyceride MetabolismCONTENTSFATTY ACID METABOLISMPathway Reaction Steps in Fatty Acid Synthesis Acetyl Coenzyme A to PalmitateRegul

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