Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
Epithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1Epi Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2ithelial Cell AbnormalitiesSquamous Cell•Squamous Intraepithelial Lesion (SIL)-Low-grade squamous intraepithelial lesion (LSIL)-High-grade squamous intraepithelial lesion (HSIL)• With features suspicious for invasion (if invasion is suspected)•Squamous cell carcinomaM.R. Henry. MD (EJ)Department of Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2Laboratory Medicine. Mayo Clinic. 200 1st Street sw. Rochester.MN 55905. USAe-mail: henry.michael@mayo.eduD.K. Russell. CTtASCPtHT. MEdDepartment of PEbook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
athology and Laboratory Medicine. University of Rochester Medical Center.601 Elmwood Avenue, 626, Rochester. NY 14642. USAe-mail: donna_russell@urmc.rEpithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1Epi Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2diagnostics.comM.u. Prey. MD8829 Ladue Road. Ladue. Missouri 63124, USAe-mail: marianne@extravirginoo.comT.c. Wright Jr. MDDepartment of Pathology and Cell Biology. Columbia University.631 w 168th St. New York. NY 10032. USA e-mail: tcwl @cumc.columbia.eduR. Nay ar. MDDepartment of Pathology. Feinbe Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2rg School of Medicine. Northwestern University. Northwestern Memorial Hospital. 251 East Huron Street. Gaiter Pavilion. 7-I32B. Chicago. IL 60611. USAEbook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
e-mail: r-nayar@northwestem.edu© Springer International Publishing Switzerland 2015135R. Nayar. D.c. Wilbur (eds.). The Bethesda System for ReportingEpithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1Epi Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2s encompass the spectrum of noninvasive cervical epithelial abnormalities associated with human papillomavirus (HPV), ranging from the cellular changes that are associated with transient HPV infection to those representing high-grade precursors, to invasive squamous cell carcinoma. It has now been w Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2ell established that HPV is the main causal factor in the pathogenesis of virtually all cervical cancer precursors and invasive cancers [1Ị. The majorEbook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
ity of invasive cervical cancers and their precursors contain HPV types referred to as “high-risk" HPVs (hrHPV), the most common being HPV 16 [2]. OurEpithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1Epi Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2ctions generally regress over the course of 1-2 years [3, 4], and lesions with HPV persistence are associated with an increased risk of developing a cancer precursor (precancer) or invasive cancer [5-7]. This concept led to the introduction of the two-tiered nomenclature of low-grade squamous intrae Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2pithelial lesion (LSIL) and high-grade squamous intraepithelial lesion (HSIL), by the Bethesda System (TBS) in 1988.In 2012, (he Lower Anogenital SquaEbook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
mous Terminology Standardization Consensus Conference (LAST) adopted a two-tiered nomenclature, mirroring the Bethesda SIL classification, for the hisEpithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1Epi Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2s cell precursors also advocated the Use of a two-tiered classification system [9]. The basis of these recommendations was the fact that HPV-related lesions of the lower anogenital, both mucosal and cutaneous, have similar biology and accompanying risks for development of invasive carcinoma and shou Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2ld be managed similarly. In TBS for cytology and LAST/WHO for histopathology. LS1L encompasses the cellular changes associated with the older terms ofEbook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
koilocytosis. mild dysplasia, and CIN I, while HSIL encompasses the more clinically significant lesions previously termed moderate and severe dysplasEpithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1Epi Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2n considerations. First was the desire to use morphologic categories that relate to the biology and clinical management of HPV-associated lesions as outlined above, and second was the acknowledged low inter- and intraobserver reproducibility with three- and four-grade classification systems [10, II] Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2. Then and since, it has been argued that a two-tiered system provides less information to clinicians than a three-tiered CIN terminology [12]. HoweveEbook The Bethesda system for reporting cervical cytology (3rd edition): Part 2
r, the cytologic distinction of CIN 2 and CIN 3 is poorly reproducible, and combining the cytologic correlates of biopsy-confirmed CIN 2 and CIN 3 intEpithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1Epi Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2other concern voiced about the two-tiered classification is that the dividing line between low-grade and high-grade precursors should be set between CIN 2 and CIN 3 because the natural history of untreated CIN 2 is closer to that of CIN I than it is to CIN 3 [13]. In some European countries. CIN I a Ebook The Bethesda system for reporting cervical cytology (3rd edition): Part 2nd CTN 2 are grouped together for treatment purposes [12|.5 Epithelial Cell Abnormalities: Squamous137Epithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1EpiEpithelial Cell Abnormalities: SquamousMichael R. Henry, Donna K. Russell, Ronald D. Luff, Marianne u. Prey, Thomas c. Wright Jr, and Ritu Nayar5.1EpiGọi ngay
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