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Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

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Nội dung chi tiết: Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis esis submitted in partial fulfillment of the requirements for the degree ofDoctor of PhilosophyinBiomedical EngineeringDepartment of Biomedical Engine

ering University of Alberta'£• Quang N. Vo. 2016AbstractAdolescent idiopathic scoliosis (ATS) is a three-dimensional (3D) spinal deformity with unknow Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

n causes and with prevalence of 1.5 - 3% of adolescents. If AIS is left untreated, it may progress, leading to back pain, cardiopulmonary problems, an

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

d psychosocial concerns, and eventually resulting in surgical intervention. Four types of scoliosis treatment exist and the selection of management de

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis two-dimensional (2D) postero-anterior (PA) radiograph. However, this 2D measurement may underestimate the true severity of scoliosis, which affects t

reatment decisions. To report the acmal severity, the Cobb angle on the plane of maximum curvature (PMC) must be measured, requiring a 3D spinal image Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

. Although X-ray' based imaging modalities such as computed tomography (CT) and multi-planar radiography provide good 3D images of the spine, the cumu

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

lative amount of ionizing radiation increases the risk of cancer. Therefore. 3D ultrasound was proposed in this PhD research as an alternative imaging

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis m (he ultrasound images.Io reconstruct 3D spinal images from 2D B-scans (B-modc images), a software was developed using the voxel-based reconstruction

method with bi-linear interpolation. This software could also measure the AVR. the Cobb angle and the lateral deviation on the PA plane and the PMC.T Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

n order to obtain an optimal reconstructed image, in-virro and in-vivo experiments were performed to investigate the optimal ultrasound configurations

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

that consisted of the iiultrasound frequency, the minimum spacing between two adjacent B-scans, and the reconstruction resolution. From both in-vitro

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis the best results.To measure the AVR. the Cobb angle and the lateral deviation on the PA plane and the PMC. the centre-of-lamina method was used. In-v

itro and in-vivo studies were performed and the results demonstrated that the intra- and inter-rater reliabilities were high for all five parameters ( Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

ICC > 0.90). In addition, the Cobb angle measurements from the PA ultrasound images agreed well with the Cobb angle measurements from scoliosis clinic

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

s with a small variation (MAD < 3°) and high correlation (ICC > 0.90). The measurements of the lateral deviations also showed high reliabilities (ICC

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis d 7°. This result agreed with reports from literature. In addition, the AVR from the in-vitro study showed a strong correlation and high agreement bet

ween the ultrasound and CT images (ICC > 0.90. MAD < 2°). Unfortunately, the in-vivo intervertebral rotations reported from the EOS system did not mat Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

ch to the ultrasound measurements. Further studies will be required to understand the reasons for the discrepancies.Since the 3D ultrasound was able t

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

o provide true spinal deformity information, a study to investigate which demographic and 3D ultrasound parameters correlated with the progression of

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis rated the PMC Cobb angle and the number of vertebrae within the largest curve were the most reliable predictors. A preliminary validation using 6 subj

ects was performed. The variationiiibetween the measured and the predicted Cobb angles was 2.9° ± 1.3°. The adjusted r2 was 0.87. indicating a good fi Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

t of data to the model.In conclusion, this PhD thesis demonstrated that the 3D freehand ultrasound method could be used to reconstruct 3D images of th

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

e scoliotic spine. The AVR. the PMC Cobb angle and lateral de\ ialion could be measure reliably to assess the true severity of AIS. The PMC Cobb angle

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis thesis is an original intellectual product of the author, Quang N. Vo. The research described in this thesis received ethics approval from the Health

Research Ethics Board of the University of Alberta with the project name: "Using ultrasound to assess spinal deformity for AIS", reference number: Pr Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

o00005707. starting January 22. 2010.Portions of the material in this thesis have been published in the following papers:•VO. Q.N. LOU. E. LE, L.H. 20

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

14. Investigation of the optimal freehand three-dimensional ultrasound configuration to image scoliosis: An in-vitro study. In: Vo. T. V. & Tran, p. H

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis e materials described in this conference paper are reported in Chapter 4. I perceived, executed, and composed the manuscript of the work described in

the paper. Dr. Lou endorsed technical advice and direction, and assisted with manuscript preparation. Dr. Le edited the manuscript.•VO. Q.N. LOU. E. L Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

E. L.H. 2015. Measurement of axial vertebral rotation using three-dimensional ultrasound images. Scoliosis and Spinal Disorders. 10. 1-4.The materials

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

from this journal article are also reported in Chapter 4. I was responsible for conducting the experiment, acquiring data, developing the software, p

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis 014. Reconstruction of a scoliotic spine using a three-dimensional medical ultrasound system. The 10th meeting of the International Research Society o

f spinal Deformities, Sapporo. Japan, June 29 - July 2 2014.Part of the materials from this conference abstract is included in Chapter 4 of this thesi Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

s. I conceived of and executed the work from designing and conducting the experiment, collecting data, developing the software, performing measurement

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

s, and analyzing the results. I composed the abstract with assistance from Dr. Lou and Dr. Le.Vvo, Ọ.N. LOU. E. LE. L.H. 2015. 3D ultrasound imaging m

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis aly. August 25-29 2015. 1540-3.The materials from this conference paper are reported in Chapter 4. I contributed to design the experiment, collecting

data, developing the software, performing measurements, and analyzing the results. I composed the manuscript with assistance from all co-authors. Reliability of three dimensional ultrasound parameters and their correlation with the progression of adolescent idiopathic scoliosis

Reliability of Three-dimensional Ultrasound Parameters and Their Correlation with the Progression of Adolescent Idiopathic ScoliosisbyQuang N. VoA the

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