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Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

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Nội dung chi tiết: Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis apy Associated With Improved Thrombus Resolution In Patients With Deep Vein ThrombosisCharles HsuFollow this and additional works at: https://elischol

ar.library.yale.edu/ymtdlRecommended CitationHsu. Charles, ‘Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thr Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

ombosis’ (2020). Yale Medicine Thesis Digital Library. 3911.https://elischolar.library.yale.edu/ymtdl/3911This Open Access Thesis is brought to you fo

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

r free and open access by the School of Medicine at EliScholar - A Digital Platform for Scholarly Publishing at Yale. It has been accepted for inclusi

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis e information, please contact elischo!ar@yale edu.Statin Therapy Associated with Improved Thrombus Resolution in Patients with Deep Vein ThrombosisA T

hesis Submitted to theYale University School of Medicine in Paitial Fulfillment of the Requirements for the Degree of Doctoi in MedicineByChai les Hsu Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

20201AbstractObjectives: Statin therapy has been associated with a decreased incidence of venous thromboembolism (VTE) in clinical trials and enhanced

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

thrombus resolution in annual models. The effect of statins on thrombus resolution has not been reported clinically. This study investigates the asso

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis ic medical records of consecutive adult patients presenting with lower extremity DVT was performed. Patients were divided into two groups based on sta

tin therapy (statin group) or lack thereof (non-statin group). The two groups were compared with respect to demographics, comorbidities, and risk fact Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

ors for VTE. Initial as well as all subsequent ultrasound reports were reviewed for each patient to determine extent of DVT and subsequent change in t

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

hrombus characteristics. Long-term outcomes examined were thrombus improvement or resolution on follow up ultrasound. \TE recurrence, mortality. Multi

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis of 818 patients with DV1 were identified [statin gloup: n 279 (31%), non-statin group: n = 539 (66%)J. The patients in the statin group were significa

ntly older (P < .001). Patients on statin were more likely to have risk factors for and manifestations of atherosclerosis and to be on antiplatelet th Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

erapy (P < .001) while those in the non-statin group were more likely to have a hypercoagulablc disorder (P .009) or prior DV T (P2= .033). There was

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

no significant difference in provoked DVT. extent of DVT. or association with PE (pulmonary embolus), but patients on statin were more likely to have

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis er placement, or treatment with lytic therapy. There was no difference in thrombus resolution, mortality, or recurrence of DVT. PE. or VTE between the

gloups. On multivariable analysis, age, proximal DVT. CAD. and cancer were associated with higher mortality while anticoagulation with warfarin and D Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

OACs and antiplatelet therapy were associated with lowei mortality Statin therapy, antiplatelet therapy and younger age were associated with thrombus

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

resolution or improvement.Conclusions: Statin therapy is associated with gieater tluombus resolution or improvement in patients with DVT However, stat

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis nder the guidance of Cassius Iyad Ochoa Clraar. MD. MS.Associate Professor of Surgery, the Division of Vascular Surgery. Department ofSurgery. Yale Un

iversity School of Medicine. Other contributors to this work includeAnand Brahrnandam. MD. Kirstyn E Brownson. MD. Nancy Huynh. MD. JesseReynolds. MS. Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

Alfred I Lee. MD. PhD. and Wassim H Fares. MD. MSc. Contributions are described in detail in the Methods sectionThis work was made possible by the gr

Luận văn Thạc sĩ Statin Therapy Associated With Improved Thrombus Resolution In Patients With Deep Vein Thrombosis

ant from the National Heart. Lung and Blood

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

Yale UniversityEliScholar - A Digital Platform for Scholarly Publishing at YaleYale Medicine Thesis Digital LibrarySchool of Medicine43831Statin Thera

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