management of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
➤ Gửi thông báo lỗi ⚠️ Báo cáo tài liệu vi phạmNội dung chi tiết: management of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
management of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
Accepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 ye management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionsears and future directionsRunning title -Post-Traumatic Epilepsy (PTE) managementKeywords - traumatic brain injury, epilepsy, late seizures, management, communityLoretta Piccenna BSc (Hons) PhD1 *, Graeme Shears1, Terence J O'Brien MBBS, MD, FRACP, FRCPEJ1The Epilepsy Foundation, Melbourne, Victoria management of post traumatic epilepsy pte an evidence review over the last 5 years and future directions, Australia2Department of Medicine, The University of Melbourne, Victoria, Australia3James Stewart Professor of Medicine, Deportment of Medicine, Themanagement of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
University of Melbourne, The Royal Melbourne Hospital Victoria, AustraliaCorresponding Author:Loretta Piccenna,Epilepsy Foundation,587 Canterbury RoadAccepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 ye management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionslication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002. epi4.12049This article is protected by copyright management of post traumatic epilepsy pte an evidence review over the last 5 years and future directions. All rights reserved.Key points -•There is no evidence for the effectiveness of pharmacological treatments in the prevention or treatment of symptomamanagement of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
tic seizures in adults•Limited high level evidence for the effectiveness of levetiracetam was identified for children with PTE•Promising low-level eviAccepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 ye management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionsic targets are necessary for the management of PTEAbstractPost-traumatic epilepsy (PTE) is a relatively underappreciated condition that can develop as a secondary consequence following traumatic brain injury (TBI). The aim of this rapid evidence review is to provide a synthesis of existing evidence management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionson the effectiveness of treatment interventions for the prevention of PTE in people who have suffered a moderate/severe T8I to increase awareness andmanagement of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
understanding among consumers. Electronic medical databases (n=5) and grey literature published between January 2010 and April 2015 were searched for Accepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 ye management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionsness of any pharmacological treatments in the prevention or treatment of symptomatic seizures in adults with PTE. However, limited high-level evidence for the effectiveness of the anti-epileptic drug levetiracetam was identified for PTE in children. Low-level evidence was identified for non-pharmaco management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionslogical interventions in significantly reducing seizures in patients with PTE, but only in a minority of cases, requiring further high-level studies tmanagement of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
o confirm the results. This review provides an opportunity for researchers and health service professionals to better understand the underlying pathopAccepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 ye management of post traumatic epilepsy pte an evidence review over the last 5 years and future directions protected by copyright. All rights reserved.IntroductionPost-Traumatic Epilepsy (PTE) is a serious and disabling delayed consequence of a traumatic brain injury (TBI). PTE is one of the most common types of acquired (or secondary) epilepsies, which are due to a brain insult, e.g. trauma, tumours, s management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionstroke, and infections, accounting for 20% of acquired epilepsy in the general population 1;?. People with PTE commonly experience a latent or silent pmanagement of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
eriod of at least 6 months, and sometimes up to 20 years, between the causative injury and the onset of seizures, providing a potential time window foAccepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 ye management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionsstory and clinical heterogeneity for appropriate treatment to be provided at the right time.Insert PiccennaFigure 1 hereIncidence and Risk FactorsPTE has been described as a particularly heterogeneous condition, in particular due to the heterogeneity associated with TBI. The types of seizures experi management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionsenced by people with PTE are focal onset seizures with or without secondary generalisation to bilateral tonic-clonic convulsive activity, with some exmanagement of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
periencing focal non-convulsive seizures only Early seizures are often of the generalised tonic-clonic convulsive type, in comparison to late seizuresAccepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 ye management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionsis of the relative risk (RR) for unproved seizures by Herman (2002) reported that severe TBI confers a RR 29 times that of the general population, whilst for mild and moderate TBI it was 1.5 and 4, respectively3. Within the first 2 years following TBI, it has been found that the risk of PTE is the h management of post traumatic epilepsy pte an evidence review over the last 5 years and future directionsighest ’. However, the risk of developing PTE is still high >10 years in people with moderate TBI and >20 years in people With severe TBI5. Hence, Itmanagement of post traumatic epilepsy pte an evidence review over the last 5 years and future directions
is not unusual for cases of PTE to occur 30-35 yearsThis article is protected by copyright. All rights reserved.Accepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 yeAccepted Date : 07-Feb-2017Article type : Critical ReviewTitle page:Management of Post-Traumatic Epilepsy (PTE): an evidence review over the last 5 yeGọi ngay
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